Results 61 to 70 of about 5,806,032 (291)

A Study of Clinicohistopathological Correlation in Patients of Hansen Disease

Nepal Journal of Dermatology, Venereology & Leprology
Background: Hansen's disease (Leprosy), caused by Mycobacterium leprae, is a chronic granulomatous condition with varied clinical presentations reflecting the host's immune response.
Manish Pradhan, Anjan Rai, Sunita Karki, Srijana KC   +3 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Hodgkin transformation of chronic lymphocytic leukemia/small lymphocytic lymphoma [PDF]

Vojnosanitetski Pregled
Introduction. In rare cases, chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma may transform into Hodgkin lymphoma, with about a hundred cases reported in the literature so far.
Vučić Miodrag, Lilić Božidar, Stojnev Slavica, Krstić Miljan   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Ecotoxicological consequences of heavy metals on emperor fish (lethrinus) species in the red sea: histopathology and biochemistry [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi
Heavy metal (HMs) contamination in marine environments is a global concern, affecting fish health and seafood safety. This study examined the effects of HMs on 90 emperor fish from the Red Sea, focusing on metal levels in water and fish liver, blood ...
Soha A. ALSOLMY, Raoum MOMINKHAN, Sahar J. MELEBARY   +2 more
doaj   +1 more source

The determination of specificity, sensitivity and accuracy of core needle biopsy in the diagnosis of parotid and submandibular salivary glands tumors [PDF]

Vojnosanitetski Pregled, 2019
Background/Aim. The diagnosis of tumors of salivary glands relies heavily on radiological examination and biopsy of pathological tissue. The aim of this study was to investigate the sensitivity, specificity and accuracy of core needle biopsy in diagnosis
Oroz Aleksandar, Bokun Zorana, Antonijević Đorđe, Jevđić Jasna   +3 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

PARTICULARITIES OF THE MANAGEMENT OF THE HISTOLOGY LABORATORY [PDF]

Annals of the University of Craiova: Economic Sciences Series, 2019
The managerial process in the health field is an extremely complex one, because it presents besides the basic components of an organizational system and the human component: the patient.
Oprea-Valentin BUSU , Cristina-Elena ANDREI   +1 more
doaj  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Prevalence of Helicobacter pylori Infection in Gallbladder Specimens of Patients with Calculous Cholecystitis: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Helicobacter pylori (H. pylori) infection is highly prevalent in developing countries and is well known for its role in gastroduodenal diseases. In recent years, its possible association with extra-gastric disorders, including hepatobiliary
SB Vasanthbalan, Magesh Chandran, S Madan, Ajay Gokul, Kuberan Krishnan   +4 more
doaj   +1 more source