Results 181 to 190 of about 2,296,408 (307)

In Vivo Monitoring of Thrombo‐Inflammatory Biomarkers via Molecularly Imprinted Polymer‐Integrated Hydrogel Microneedles

open access: yesAdvanced Materials, EarlyView.
A wearable electrochemical microneedle patch integrates Prussian Blue redox transduction with molecularly imprinted polymer recognition for reagent‐free sampling and detection of thrombo‐inflammatory biomarkers in dermal interstitial fluid. The platform tracks thrombin and inflammatory cytokines with sensitive in vitro, ex vivo, and in vivo performance,
Mahmoud Ayman Saleh   +11 more
wiley   +1 more source

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

open access: yesAdvanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab   +8 more
wiley   +1 more source

Ionizable Lipid‐Dependent Optimization of Steroid Lipid Nanoparticles With Tunable Immunomodulatory Properties

open access: yesAdvanced Materials, EarlyView.
A novel engineering strategy that establishes material design principles for incorporating anti‐inflammatory steroids into lipid nanoparticles to reduce LNP‐induced inflammation while retaining mRNA delivery. Results are validated in vitro and in three animal models of inflammation and autoimmunity in vivo.
Ajay S. Thatte   +21 more
wiley   +1 more source

Ultrathin Hydrogel Membranes Inspired by Soap Films Enable Physiologically Relevant Breathing Lung Models

open access: yesAdvanced Materials, EarlyView.
A soap‐film inspired strategy enables the fabrication of ultrathin yet robust GelMA‐PAAm membranes for breathing lung culture. The hydrogel membrane supports long‐term cyclic deformation under air‐liquid interface conditions, enabling physiologically relevant breathing motions of engineered lung tissue culture. ABSTRACT Breathing continuously stretches
Yunji Lee   +9 more
wiley   +1 more source

Paired CycleGAN-based virtual staining for 3D X-ray histology of bone-implant systems. [PDF]

open access: yesJ Synchrotron Radiat
Irvine SC   +5 more
europepmc   +1 more source

Metal–Organic Framework‐Preserved Thermostable Microneedle Patch for Minimally Invasive Detection and Monitoring of Kidney Dysfunction

open access: yesAdvanced Materials, EarlyView.
By growing a conformal ZIF‐8 protective layer directly on antibody‐functionalized microneedles, this work converts a fragile biosensing interface into a thermostable diagnostic platform. The MOF@MN patch enables minimally invasive NGAL detection from dermal ISF while supporting cold‐chain‐independent storage and transport for decentralized kidney ...
Yixuan Wang   +10 more
wiley   +1 more source

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