Results 81 to 90 of about 207,989 (291)

Potential therapeutic effects of shrimp protein hydrolysates on NAFLD-induced infertility disorders: Insights into redox balance, heat shock protein expression, and chromatin compaction in male rats [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): Nonalcoholic fatty liver disease (NAFLD) is known to disrupt testicular anti-oxidant capacity, leading to oxidative stress (OS) that can negatively affect male fertility by damaging sperm DNA.
Somayyeh Rahmani, Ebrahim Najdegerami, Mazdak Razi, Mehdi Nikoo   +3 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Allogeneic Stem Cells Alter Gene Expression and Improve Healing of Distal Limb Wounds in Horses. [PDF]

, 2017
Distal extremity wounds are a significant clinical problem in horses and humans and may benefit from mesenchymal stem cell (MSC) therapy. This study evaluated the effects of direct wound treatment with allogeneic stem cells, in terms of gross, histologic,
Aristizobal, Fabio A, Bledsoe, Andrea, Bohannon-Worsley, Laurie K, Borjesson, Dori L, Clark, Kaitlin C, Davidyan, Arik, Gray, Sarah N, Kol, Amir, LeJeune, Sarah S, Textor, Jamie A, Walker, Naomi J, Woolard, Kevin D   +11 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Some Aspects of the Anatomy and Histology of Digestive Tracts in Two Sympatric Species of Freshwater Fishes

Sultan Qaboos University Journal for Science, 2003
Comparative anatomy and histology of the digestive tracts of two sympatric species of freshwater fish, Aphanius dispar (Cyprinodontidae) and Garra barreimiae (Cyprinidae) are studied.
Taher Ba-Omar, Reginald Victor, Daniel Tobias   +2 more
doaj   +1 more source

Structure and optics of the anterior segment of the cetacean eye : a thesis presented in fulfilment of the requirements for the degree of Master of Philosophy at Massey University [PDF]

, 1999
The anterior segment of the mammalian eye is concerned with the function and maintenance of its optical components, the most important of these being the maintenance of transparency and stable intraocular pressure.
Mellor, Lynda
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Comparative digital cartilage histology for human and common osteoarthritis models

Orthopedic Research and Reviews, 2013
Douglas R Pedersen, Jessica E Goetz, Gail L Kurriger, James A MartinDepartment of Orthopaedics and Rehabilitation, University of Iowa, Iowa City, IA, USAPurpose: This study addresses the species-specific and site-specific details of weight-bearing ...
Pedersen DR, Goetz JE, Kurriger GL, Martin JA   +3 more
doaj  

Mitofusin 2 in Mature Adipocytes Controls Adiposity and Body Weight

Cell Reports, 2019
Summary: We found that exposure of adult animals to calorie-dense foods rapidly abolished expression of mitofusin 2 (Mfn2), a gene promoting mitochondrial fusion and mitochondrion-endoplasmic reticulum interactions, in white and brown fat.
Giacomo Mancini, Kevin Pirruccio, Xiaoyong Yang, Matthias Blücher, Matthew Rodeheffer, Tamas L. Horvath   +5 more
doaj   +1 more source

Sodium chloride transport of normal and dietary enlarged rat cecum in vitro [PDF]

, 1998
Sodium chloride transport across isolated cecum mucosa was investigated in normal rats and rats with adaptive cecum growth induced by dietary polyethylene glycol (PEG). The normal cecum absorbed CI in excess of Na with a small short-circuit current (Isc).
Loeschke, Klaus, Schreiner, Josefine, Weber, Matthias   +2 more
core   +1 more source