Results 71 to 80 of about 2,296,408 (307)

Mitofusin 2 in Mature Adipocytes Controls Adiposity and Body Weight

Cell Reports, 2019
Summary: We found that exposure of adult animals to calorie-dense foods rapidly abolished expression of mitofusin 2 (Mfn2), a gene promoting mitochondrial fusion and mitochondrion-endoplasmic reticulum interactions, in white and brown fat.
Giacomo Mancini, Kevin Pirruccio, Xiaoyong Yang, Matthias Blücher, Matthew Rodeheffer, Tamas L. Horvath   +5 more
doaj   +1 more source

Ameliorating Effects of Vitamin E on Morphological and Histological Alterations and Oxidative Stress Factors Assessment Against Titanium Dioxide Nanoparticle-Induced in Mice Testis [PDF]

Journal of Advanced Biomedical Sciences, 2020
Background & Objectives: Nano titanium dioxide particles (TiO2) are chemical compounds that are widely used in industrial and foodstuff such as cosmetics, toothpaste, colored materials, and non-fat milk whitening.
ramin jahangirfard, ahmad reza raji, Amir moghaddam jafari, Hossein Nourani   +3 more
doaj  

Comparative Analysis of Histological Tools for Myelin

Neuroscience Bulletin
Myelin is an essential structure that facilitates rapid saltatory conduction in the nervous system. Discrepancies in myelin microstructure are a hallmark of numerous neurological disorders, rendering the assessment of myelin integrity and content an indispensable tool in clinical diagnostics and neuroscience research.
Zihui An, Shuo Yan, Jiayi Wang, Hanqing Qiu, Binghua Xie, Shumei Feng, Mengsheng Qiu, Zhou Tan   +7 more
openaire   +2 more sources

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Integrating X-ray phase-contrast imaging and histology for comparative evaluation of breast tissue malignancies in virtual histology analysis

Scientific Reports
Detecting breast tissue alterations is essential for cancer diagnosis. However, inherent bidimensionality limits histological procedures’ effectiveness in identifying these changes.
Sandro Donato, Lucia Mariel Arana Peña, Fulvia Arfelli, Luca Brombal, Luisella Colmo, Renata Longo, Fulvia Martellani, Giuliana Tromba, Fabrizio Zanconati, Deborah Bonazza   +9 more
doaj   +1 more source

A Comparative Analysis on the Histomorphometric Pattern of Various Segments of Adult Male Long Bones: Forensic Implication

Journal of Forensic Science and Medicine
Background: Human bone analysis is a useful tool in assessing and identifying skeletal remains. To make this easier, newer and modified approaches have often being documented. Aims and Objectives: The aim of this study is to analyze the histomorphometric
Clinton David Orupabo, Joshua Oghenemiro Chijioke   +1 more
doaj   +1 more source

Effect of dietary medicinal plant supplementation and aflatoxin B1 contamination on digestive enzymes activity of rainbow trout stocked at various densities [PDF]

بوم‌شناسی آبزیان, 2019
The effect of stocking density and dietary aflatoxin B1 along with rosemary and thyme powders on digestive enzymes activity was evaluated in rainbow trout.
Zahra Mahmoudikia, Ahmad Imani, Kourosh Sarvi Moghanlou, Mazdak Razi   +3 more
doaj  

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Clinical parameters, histological analysis, and laser Doppler flowmetry of different subepithelial connective tissue grafts

Journal of Indian Society of Periodontology, 2018
Subepithelial connective tissue graft (SCTG) presents favorable outcomes. However, the harvesting technique can influence the anatomical and histological composition of the SCTG.
Ricardo Rabelo Eustachio, Rafael Ferreira, Nair Cristina Margarida Brondino, Carla Andreotti Damante, Maria Lucia Rubo De Rezende, Adriana Campos Passanezi Sant'ana, Sebastião Luiz Aguiar Greghi, Mariana Schutzer Ragghianti Zangrando   +7 more
doaj   +1 more source