Results 121 to 130 of about 166,900 (293)
Chondrocyte Heterogeneity; It Is the Time to Update the Understanding of Cartilage Histology [PDF]
Chondrocytes were described as one cell populations in most cartilage literature. Two different chondrocyte populations; dark and light, were described in the articular cartilage and a third population, adipochondrocytes, was described in the elastic cartilage.
arxiv
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy+14 more
wiley +1 more source
CLIP-IT: CLIP-based Pairing for Histology Images Classification [PDF]
Multimodal learning has shown significant promise for improving medical image analysis by integrating information from complementary data sources. This is widely employed for training vision-language models (VLMs) for cancer detection based on histology images and text reports.
arxiv
Hydrogen sulfide repairs testicular damage induced by heat stress in rats
Heat stress can cause testicular damage and affect fertility. We investigated the potential protective role of hydrogen sulfide (H2S) against heat stress‐induced testicular injury and observed that H2S donor NaHS can effectively restore testicular damage in rats by inhibiting inflammation and oxidative stress. Our results suggest that H2S might be used
Xinyu Guo+6 more
wiley +1 more source
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei+6 more
wiley +1 more source
A COMPARATIVE HISTOLOGIC AND IMMUNOLOGIC STUDY IN RABBITS OF INDUCED HYPERSENSITIVITY OF THE SERUM SICKNESS TYPE [PDF]
Frederick G. Germuth
openalex +1 more source
William Bloom, Alexander A. Maximow
openaire +3 more sources
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik+3 more
wiley +1 more source
LatentArtiFusion: An Effective and Efficient Histological Artifacts Restoration Framework [PDF]
Histological artifacts pose challenges for both pathologists and Computer-Aided Diagnosis (CAD) systems, leading to errors in analysis. Current approaches for histological artifact restoration, based on Generative Adversarial Networks (GANs) and pixel-level Diffusion Models, suffer from performance limitations and computational inefficiencies.
arxiv
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang+9 more
wiley +1 more source