Results 131 to 140 of about 1,108,608 (357)

Dietary mannanoligosaccharide influenced feed consumption and gut morphology of Nile tilapia raised in net-cage systems

open access: yesBoletim do Instituto de Pesca, 2018
This work was set out to determine the effects of increasing levels of dietary mannanoligosaccharides (MOS) on growth and intestine morphology of Nile tilapia. Individuals (12.3 ± 0.3 g) were randomly distributed into 16 net-cages (250 L; 20 fishes per
Ricardo Yuji SADO   +4 more
doaj  

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao   +7 more
wiley   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

open access: yesFEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee   +3 more
wiley   +1 more source

Therapeutic Potential of Tanshinones in Osteolytic Diseases: From Molecular and Cellular Pathways to Preclinical Models

open access: yesDentistry Journal
Tanshinones are a class of lipophilic diterpenoid quinones extracted from Salvia miltiorrhiza (Dan shen), a widely used herb in traditional Chinese medicine. These compounds, particularly tanshinone IIA (T-IIA) and sodium tanshinone sulfonate (STS), have
Rafael Scaf de Molon
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Organization and micromorphology of the ovo-spermathecal apparatus in earthworm Eudrilus eugeniae (Crassiclitellata, Eudrilidae) with a particular emphasis on the ovary and ovisac

open access: yesThe European Zoological Journal
The family Eudrilidae is remarkable among other earthworms for the occurrence of internal fertilization. Also, the female reproductive system in this family is unique due to the evolutionary tendency to unify individual elements into a complex system ...
D. Raś, A. J. Phillips, P. Świątek
doaj   +1 more source

The Associations Between Chronic Active Lesions and White Matter Disease: A 7 Tesla Imaging Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The relationship between paramagnetic rim lesions (PRLs) and surrounding normally appearing white matter (NAWM) disease, potentially contributory to the associations seen between PRLs and clinical impairment, is underexplored. Objectives To assess whether PRLs correlate with a greater degree of NAWM injury in early MS.
Ellie McCluey   +17 more
wiley   +1 more source

Rutin and Moringa oleifera leaf extract prevent monosodium glutamate-induced testicular toxicity in adult male albino rats

open access: yesFrontiers in Veterinary Science
IntroductionMonosodium glutamate (MG) is a substance often used to enhance food flavor, but its effect on the reproductive system is known to have a negative impact.
Doaa M. Abdel-Aty   +7 more
doaj   +1 more source

The Histology of the Eye [PDF]

open access: yesThe Monthly Microscopical Journal
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openaire   +2 more sources

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