Results 131 to 140 of about 40,662 (194)

Choreography of methylation: KDM4C histone demethylation enables ALKBH5 m6A RNA demethylation to sustain AML stem cells. [PDF]

Blood Sci, 2020
Sarma P, Plas DR.
europepmc   +1 more source

Arabidopsis TRB Proteins Form Two Closely Related Complexes to Mediate H3K4me3 Demethylation and Transcriptional Repression

Advanced Science
The Arabidopsis telomere repeat binding proteins TRB1, TRB2, and TRB3 (TRB1/2/3) are components of the PWWP‐EPCR‐ARID‐TRB (PEAT) complex, which is involved in histone acetylation and H2A deubiquitination.
Qi Wang, Dan‐Yang Yuan, Yu‐Jia Lu, Xin Wang, Hao Zheng, Lin Li, She Chen, Xin‐Jian He   +7 more
doaj   +1 more source

Epstein-Barr virus hijacks histone demethylase machinery to drive epithelial malignancy progression through KDM5B upregulation

Signal Transduction and Targeted Therapy
Epstein-Barr virus (EBV) is a significant epigenetic driver in the development of epithelial-origin nasopharyngeal carcinoma (NPC) and gastric cancer (GC), which together represent 80% of EBV-associated malignancies.
Ya-Qing Zhou, Jia-Xin Jiang, Shuai He, Yi-Qi Li, Xi-Xi Cheng, Shu-Qiang Liu, Pan-Pan Wei, Xin-Yuan Guan, Choon Kiat Ong, Vivien Ya-Fan Wang, Chun-Ling Luo, Jin-Xin Bei   +11 more
doaj   +1 more source

Evi1 governs Kdm6b-mediated histone demethylation to regulate the Laptm4b-driven mTOR pathway in hematopoietic progenitor cells. [PDF]

J Clin Invest
Wu Q, Yu C, Yu F, Guo Y, Sheng Y, Li L, Li Y, Zhang Y, Hu C, Wang J, He TC, Huang Y, Ni H, Huo Z, Wu W, Wang GG, Lyu J, Qian Z.   +17 more
europepmc   +1 more source

Targeting P16INK4A in uterine serous carcinoma through inhibition of histone demethylation. [PDF]

Oncol Rep, 2019
Xiao Z, He Y, Liu C, Xiang L, Yi J, Wang M, Shen T, Shen L, Xue Y, Shi H, Liu P.   +10 more
europepmc   +1 more source

HDMs demethylate histones

Reactome - a curated knowledgebase of biological pathways, 2014
openaire   +1 more source

Vitamin C's essential role in DNA and histone demethylation and a preclinical rationale for its therapeutic high-dose potential in renal cell carcinoma. [PDF]

Ann Transl Med, 2019
Huang CH, Chang CC.
europepmc   +1 more source

Lysine-241 Has a Role in Coupling 2OG Turnover with Substrate Oxidation During KDM4-Catalysed Histone Demethylation. [PDF]

Chembiochem, 2018
Hancock RL, Abboud MI, Smart TJ, Flashman E, Kawamura A, Schofield CJ, Hopkinson RJ.   +6 more
europepmc   +1 more source

The cancer driver genes IDH1/2, JARID1C/ KDM5C, and UTX/ KDM6A: crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism. [PDF]

Exp Mol Med, 2019
Chang S, Yim S, Park H.
europepmc   +1 more source

Tolerance of DNA Replication Stress Is Promoted by Fumarate Through Modulation of Histone Demethylation and Enhancement of Replicative Intermediate Processing in Saccharomyces cerevisiae. [PDF]

Genetics, 2019
Saatchi F, Kirchmaier AL.
europepmc   +1 more source