Results 301 to 310 of about 317,398 (334)

Fantastic proteins and where to find them - histones, in the nucleus and beyond.

J Cell Sci
Grinat J, Shriever NP, Christophorou MA.
europepmc   +1 more source

Precision-edited histone tails disrupt polycistronic gene expression controls in trypanosomes

Novotná M, Tinti M, Faria JRC, Horn D.
europepmc   +1 more source

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Histone Acetylation and Histone Deacetylation

Molecular Biotechnology, 2002
Regulation of inflammatory gene transcription is controlled, at least in part, by the degree of local unwinding of nucleosomal DNA. This unwinding is regulated by histone acetylation--increased acetylation results in a more loosely wound structure allowing access of basal transcription factors and RNA polymerase II.
Kazuhiro Ito, Ian M. Adcock
openaire   +2 more sources

Chromatin structure: a repeating unit of histones and DNA.

Science, 1974
ciations of the histones in chromatin but says nothing of details, such as whether the F2A1 and F3 pair, which occurs as an (F2Al)2(F3)2 tetramer in solution, also occurs as a tetramer in chromatin.
R. Kornberg
semanticscholar   +1 more source

Antibodies to Histones and Histone-Histone Complexes: Immunochemical Evidence for Secondary Structure in Histone 1

Science, 1976
Highly specific antibodies were raised to histone 1 (H1) and the histone complexes H3 2 -H4 2 and H2A-H2B, isolated by salt extraction. Antibody to H1 could detect irreversible conformational changes in acid- or urea-treated H1. The antibodies showed different reactivities with chromosomes as
Orlando J. Miller, Nicholas Mihalakis, Bernard F. Erlanger   +2 more
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Yeast inner histones and the evolutionary conservation of histone-histone interactions

Biochemistry, 1978
The inner histones of the yeast, Saccharomyces cerevisiae, have been isolated and identified by their amino acid compositions. H4 appears to be close to its calf and pea counterparts. H2a, H2b, and H3 have diverged. The isolation of the histones was accomplished by consecutive slab-gel fractionation, and a number of novel features of the method are ...
James K.W. Mardian, Irvin Isenberg
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Histone Variants and Histone Modifications in Neurogenesis

Trends in Cell Biology, 2020
During embryonic brain development, neurogenesis requires the orchestration of gene expression to regulate neural stem cell (NSC) fate specification. Epigenetic regulation with specific emphasis on the modes of histone variants and histone post-translational modifications are involved in interactive gene regulation of central nervous system (CNS ...
Mengtian Zhang, Jianwei Jiao, Yuqing Lv, Libo Su, Chao Feng, Wenzheng Zou, Wenwen Wang, Wenwen Wang, Jinyue Zhao   +8 more
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Trypanosomatid histones

Molecular Microbiology, 2004
SummaryThe histones are responsible for packaging and regulating access to eukaryotic genomes. Trypanosomatids are flagellated protists that diverged early from the eukaryotic lineage and include parasites that cause disease in humans and other mammals.
Alsford, Sam, Horn, David
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Archaeal histones and the origin of the histone fold

Current Opinion in Microbiology, 2006
Histone sequences have been identified in many archaeal genomes and in environmental samples, and they constitute a family of proteins that are structural homologs of the eukaryotic core histones. Most archaeal histones conform to the single histone-fold structural models that have been described, but a few histone variants exhibit short insertions ...
John N. Reeve, Kathleen Sandman
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