Results 71 to 80 of about 16,258,523 (358)

Lysyl oxidases expression and histopathological changes of the diabetic rat nephron

Molecular Medicine Reports, 2017
Diabetic nephropathy (DN) is a major complication of diabetes, the accumulation of extracellular matrix (ECM) is considered an indication of nephropathological changes. Lysyl oxidases (LOXs) are also associated with ECM.
Jun Chen, Jie Ren, W. Loo, L. Hao, Min Wang   +4 more
semanticscholar   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

The Study of Histopathological Changes in Some of Intermediate Hosts Infected With Cystic Echinococcosis

مجلة علوم ذي قار, 2019
The present study aimed to investigate the histopathological changes in liver and lung of sheep, cattle and buffaloes, spleen of cattle and lung of human infected with cystic echinococcosis (Hydatidosis).
Wesam Jasim Hansh
doaj   +4 more sources

Using Histopathological Change as Bioindicator for Hydrocarbon Toxicity in Chick Embryo [PDF]

Journal of Bioscience and Applied Research
Histopathology studies the microscopic alteration of cells in tissue organs of living beings. Because of their economic significance and ability to be used as a model to predict the sensitivity of wild bird species to chemical contamination, chickens ...
Sarab Mustafa, Milad Husain, Estabraq Abdul lateef, Suha Ali, Noura Abed   +4 more
doaj   +1 more source

TOXOPATHOLOGICAL EFFECTS OF PHENYLMETHANE ON MALE ALBINO MICE INTERNAL ORGANS

The Iraqi Journal of Agricultural science, 2021
This study was aimed  to evaluate the toxic properties of phenylmethane on internal organs and liver enzymes (Alkaline phosphatase (ALP) and Alkaline serum transaminase (AST)changes in mice. Thirty albino mice randomly divided equally into 2 groups, each
B. I. Alkaisie, S. L. Hassan, S. A. Radam   +2 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Effects of Pasteurella multocida on Histopathology, miRNA and mRNA Expression Dynamics in Lung of Goats

Animals, 2022
Pasteurella multocida (Pm) infection causes severe respiratory disease in goats. We investigated the effects of the Pm infection intratracheally on the histopathology, miRNA and mRNA expression dynamics in the lung of goats infected for 1, 2, 5 and 7 ...
Wencan Zhang, Zizhuo Jiao, Huixian Huang, Yanru Wu, Haotian Wu, Zhiyong Liu, Zhenxing Zhang, Qi An, Yiwen Cheng, Si Chen, Churiga Man, Li Du, Fengyang Wang, Qiaoling Chen   +13 more
doaj   +1 more source

Histopathological changes in morphea and their clinical correlates: results from the Morphea in Adults and Children Cohort (MAC) V

Journal of American Academy of Dermatology, 2017
Background Histopathological features in morphea (localized scleroderma) and their clinical correlates are poorly described. Objective We sought to systematically describe histologic changes of morphea in a large, well‐annotated cohort and determine the ...
Daniel Walker, J. Susa, S. Currimbhoy, H. Jacobe   +3 more
semanticscholar   +1 more source

Histopathological changes in the knees of the five studied groups.

, 2016
Histopathological changes in the knees of the five studied groups.
Zwe-Ling Kong (790856), Yu-Chieh Lin (1982515), Jen-Hsin Kao (3095805), Sheng-Hsiung Lin (3095811), Chun-Fu Lai (141724), Chih-Shung Wong (3095808)   +5 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source