Results 81 to 90 of about 419,405 (313)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

The pathologists’ eyes on foregut: histopathological relations in the experimental and routine diagnostics [PDF]

, 2011
SUMMARY I. The study aimed to investigate the incidence of duodeno-gastroesophageal reflux-induced malignoma formation in a series of duodeno-esophageal anastomosis operations in rats.
Németh István Balázs
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Cysticercus fasciolaris (Taenia taeniaeformis Larval Stage) in Urban Rats with Illustration of Histopathological Changes in the Liver

Journal of Medical Microbiology and Infectious Diseases, 2017
Introduction: Cysticercus fasciolaris is the larval stage of the cestode Taenia taeniaeformis, whose definitive hosts are cats. Rodents and very rarely humans act as intermediate hosts.
Hamid Hasanpour, Faezeh Najafi, Mohammad Javad Gharagozlou, Sanaz Jafarpour Azami, Arezoo Fadavi, Niloofar Paknezhad, Gholamreza Mowlavi   +6 more
doaj  

Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew, Maryam Kargaran, Maik Rothe, Andreas Deistung, Dietrich Stoevesandt, Walter A. Wohlgemuth, David Strube, Thomas Kendzierski, Anna Katharina Kölsch, Maurits Gerhard Abraham Heuschen, Markus Otto, Alexander Mensch   +11 more
wiley   +1 more source

Effect of vitamin C and quercetin treatment on the liver histopathologic profile in congenital lead exposed male rat pups [PDF]

, 2015
Introduction: Lead is one of the most important environmental pollutants due to its vast use in various industries. Lead accumulation in different organs, especially the brain, liver and kidneys can cause serious health problems.
Beheshti, N., Ganji, F., Sepehri, H.
core  

Skin Cancers Among Albinos at a University Teaching Hospital in Northwestern Tanzania: A Retrospective Review of 64 Cases. [PDF]

, 2012
Skin cancers are a major risk associated with albinism and are thought to be a major cause of death in African albinos. The challenges associated with the care of these patients are numerous and need to be addressed.
A Yakubu, AN Okoro, CJ Witkop, DD Datubo-Brown, DP Lookingbill, E Berger, Erasmus Kamugisha, ES Hong, F Kagore, G Summers, GA Alexander, Geofrey Giiti, GM Edington, Hyasinta Jaka, J Luande, Japhet M Gilyoma, JG Kromberg, Joseph B Mabula, K Glanz, KO Opara, M Terenziani, Mabula D Mchembe, ME Asuquo, ME Asuquo, Nestory Masalu, Peter Rambau, Phillipo L Chalya, PL Chalya, SA Ademiluyi, SM Hutton, Ssentongo Robert, TL Diepgen, VS Ramalingam, W Fu   +33 more
core   +3 more sources

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

Trichosomoides crassicauda Infection in Laboratory Rats with Histopathological Description in the Bladder Tissue

Journal of Medical Microbiology and Infectious Diseases, 2017
Introduction: Some postgraduate students reported the presence of a nematode infection, presumably, Trichosomoides crassicauda in the urinary bladder of rats (Rattus norvegicus) from the animal house of Tehran University of Medical Sciences (TUMS).
Faezeh Najafi, Maede Taghavi Ghadikolai, Saied Reza Naddaf, Hamid Hasanpour, Iraj Mobedi, Gholamreza Mowlavi   +5 more
doaj  

Protective properties of vitamin E on hepatic cell injury caused by pregabalin on male rabbits (Biochemical and histopathological study) [PDF]

Basrah Journal of Veterinary Research
This study aimed to revel the protective properties of vitamin E on liver injury induced by pregbalin (biochemical and histopathological study) in rabbits.
Mohammed Mahmood
doaj   +1 more source