Results 141 to 150 of about 202,762 (305)

Radiographs, MRI and histopathological images of a 56-year-old female diagnosed with right knee PVNS.

open access: yes, 2015
Radiographs, MRI and histopathological images of a 56-year-old female diagnosed with right knee PVNS.
Rui-zhen Qi (709159)   +8 more
core   +1 more source

Agnuside Stabilizes the Complex I Assembly Factor NDUFAF6 to Reinforce Mitochondrial Efficiency and Thermogenic Responsiveness

open access: yesAdvanced Science, EarlyView.
ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao   +7 more
wiley   +1 more source

HistoMoCo: Momentum Contrastive Learning Pre-Training on Unlabeled Histopathological Images for Oral Squamous Cell Carcinoma Detection

open access: yes
The early detection and intervention of oral squamous cell carcinoma (OSCC) using histopathological images are crucial for improving patient outcomes. The current literature for identifying OSCC predominantly relies on models pre-trained on ImageNet to ...
Yifan He   +5 more
core   +1 more source

TRI-BCC: Tri-Level Breast Cancer Classification via Transfer Learning Networks with Histopathological Images

open access: yesMeasurement Science Review
Breast cancer (BC) is the second most common hereditary cancer in women and is most likely to affect women. The high cost of treating BC has made its prevention an important health issue.
Rajalingam Sridevi, Maruthai Kavitha
doaj   +1 more source

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

open access: yesAdvanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang   +12 more
wiley   +1 more source

Automatic annotation of histopathological images using a latent topic model based on non-negative matrix factorization

open access: yes, 2011
Histopathological images are an important resource for clinical diagnosis and biomedical research. From an image understanding point of view, the automatic annotation of these images is a challenging problem.
Fabio A González   +3 more
core   +1 more source

Histopathology Images

open access: yesJournal of Islamabad Medical & Dental College, 2021
openaire   +2 more sources

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

open access: yesAdvanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao   +14 more
wiley   +1 more source

Content-Based Histopathological Image Retrieval

open access: yesSensors
Feature descriptors in histopathological images are an important challenge for the implementation of Content-Based Image Retrieval (CBIR) systems, an essential tool to support pathologists. Deep learning models like Convolutional Neural Networks and Vision Transformers improve the extraction of these feature descriptors. These models typically generate
Camilo Nuñez-Fernández    +2 more
openaire   +3 more sources

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

open access: yesAdvanced Science, EarlyView.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo   +14 more
wiley   +1 more source

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