Results 51 to 60 of about 202,762 (305)

Radiosensitivity Prediction of Tumor Patient Based on Deep Fusion of Pathological Images and Genomics

Bioengineering
The radiosensitivity of cancer patients determines the efficacy of radiotherapy, and patients with low radiosensitivity cannot benefit from radiotherapy. Therefore, accurately predicting radiosensitivity before treatment is essential for personalized and
Xuecheng Wu, Ruifen Cao, Zhiyong Tan, Pijing Wei, Yansen Su, Chunhou Zheng   +5 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Comparative analysis of spatial and transform domain methods for meningioma subtype classification [PDF]

, 2010
Pattern recognition in histopathological image analysis requires new techniques and methods. Various techniques have been presented and some state of the art techniques have been applied to complex textural data in histological images.
Qureshi, Hammad A., Rajpoot, Nasir M. (Nasir Mahmood)   +1 more
core  

Recurrence Network Analysis of Histopathological Images for the Detection of Invasive Ductal Carcinoma in Breast Cancer

, 2023
The histopathological image analysis is one of the most crucial diagnostic procedures to identify Invasive ductal carcinoma (IDC) in breast cancers. However, this diagnosis process is currently time-consuming and heavily dependent on human expertise ...
Wang, Yujie, Hui Yang, Chen, Cheng-Bang, Yang, Hui, Cheng-Bang Chen, Yujie Wang, Fu, Xuanya, Xuanya Fu   +7 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

An Unsupervised Learning Tool for Plaque Tissue Characterization in Histopathological Images

Sensors
Stroke is the second leading cause of death and a major cause of disability around the world, and the development of atherosclerotic plaques in the carotid arteries is generally considered the leading cause of severe cerebrovascular events.
Matteo Fraschini, Massimo Castagnola, Luigi Barberini, Roberto Sanfilippo, Ferdinando Coghe, Luca Didaci, Riccardo Cau, Claudio Frongia, Mario Scartozzi, Luca Saba, Gavino Faa   +10 more
doaj   +1 more source

Deep texture representation analysis for histopathological images

STAR Protocols, 2023
Summary: Deep texture representations (DTRs) produced from a bilinear convolutional neural network allow objective quantification of tumor histopathology images effectively.
Ranny Rahaningrum Herdiantoputri, Daisuke Komura, Kei Fujisaka, Tohru Ikeda, Shumpei Ishikawa   +4 more
doaj   +1 more source

Efficient Classification of Histopathology Images

CoRR
12 pages, 2 figures, Accepted paper for the 27th International Conference on Pattern Recognition (ICPR ...
Mohammad Iqbal Nouyed, Mary-Anne Hartley, Gianfranco Doretto, Donald A. Adjeroh   +3 more
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source