Results 61 to 70 of about 326,212 (268)

Gut Microbiota Regulates Systemic Inflammatory Response and Compensatory Anti‐Inflammatory Response Syndromes by Targeting PF4+ Macrophages in Acute Pancreatitis

Advanced Science, EarlyView.
ABSTRACT Acute pancreatitis (AP) begins with pancreatic local inflammation, leading to the onset of systemic inflammatory response syndrome (SIRS), followed by compensatory anti‐inflammatory response syndrome (CARS), which causes immune paralysis and higher mortality rate.
Liwei Liu, Guanqun Li, Dongxu Lu, Haoran Ding, Tianqi Lu, Yuhang Sui, Can Zhang, Yu Xie, Rui Kong, Hua Chen, Xuewei Bai, Hongtao Tan, Dongbo Xue, Xianzhi Meng, Le Li, Bei Sun   +15 more
wiley   +1 more source

Intriguing challenging encounter of Clivus Chordoid Chordoma in a young girl: a case report

Khyber Medical University Journal
Background: Clival chordomas (CC) are rare, slow-growing tumors arising from primitive embryonic notochordal remnants, typically in the spheno-occiput, sacrococcygeal region, and clivus.
Fariha Sahrish, Alia Ahmad, Aysha Akram, Amema Hafeez, Maira Jabbar Chaudhry   +4 more
doaj   +1 more source

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

Utility of Immunohistochemistry on Cell Blocks for Detection of Malignancies using Body Cavity Fluids in a Tertiary Care Hospital

Pakistan Armed Forces Medical Journal
Objective: To determine the utility of cell block technique and immunohistochemistry in diagnosing the abdomino-pelvic and thoracic malignancies using body fluids. Study Design: Cross-sectional study.
Zainab Taj, Tariq Sarfraz, Saba Aneeqa, Rubina Riaz, Aaminah Hanif, Ghazala Rustam   +5 more
doaj   +1 more source

Estômago em melancia, pericardite hemorrágica, tumor de pequenas células do pulmão e carcinoma pavimentocelular síncrono da base da língua

Revista Portuguesa de Pneumologia, 2010
Resumo: Baseados num caso de gastropatia antral com ectasia vascular (estômago em melancia) associado a pericardite hemorrágica e a um carcinoma de pequenas células do pulmão com metástases ganglionares ao longo do mediastino e a um carcinoma ...
A. Murinello, H. Damásio, A.M. Figueiredo, J. Netta, A. Carvalho, A.A. Matos, M.J. Murillo, A. Albuquerque   +7 more
doaj   +1 more source

The Histopathology of Mastoiditis [PDF]

Proceedings of the Royal Society of Medicine, 1928
Mastoiditis, a broad term, with no strict anatomical basis, includes not only an inflammation of the pneumatic cells in the mastoid bone proper, but also all extensions into neighbouring bones (zygoma, occipitalis, etc.). Thus the anatomical distribution of the pneumatic cells plays an important part in the course of the disease. This
openaire   +2 more sources

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

Correlation of Intraoperative Frozen Section Report and Histopathological Diagnosis of Central Nervous System Tumors – A Six-Year Retrospective Study

Oman Medical Journal, 2016
Objectives: To evaluate the degree of agreement between the intraoperative frozen section (FS) reporting of central nervous system (CNS) tumors and final histopathological diagnosis based on permanent paraffin section. Methods: All CNS tumor cases with a
Radiya Al-Ajmi, Hunaina Al-Kindi, Mina George, Kurien Thomas   +3 more
doaj   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Histopathology in HCM

Global Cardiology Science and Practice, 2018
[first paragraph of article]Histopathology in patients with HCM is characterized by disarray of the overall architecture of the hypertrophied myocytes, which appear branched and may be intermingled with a variable amount of interstitial fibrosis. These changes may be patched and must be distinguished from the non-specific physiological disarrangement ...
San Millan B, Jou C
openaire   +4 more sources