Results 41 to 50 of about 326,212 (268)

Extramedullary hematopoiesis in an inguinal lymph node: an unusual presentation of primary myelofibrosis

World Journal of Surgical Oncology, 2022
Background Extramedullary hematopoiesis (EMH) is a proliferation of hematopoietic tissue outside of the bone marrow medullary space. It is a pathophysiologic response, more often associated with either a benign reactive hematological disease or a ...
Nausheen Yaqoob, Neelum Mansoor, Hania Naveed, Saba Jamal   +3 more
doaj   +1 more source

Mucinous Cystadenoma of Parotid Gland: A Rare Entity

BioMedica, 2023
Cystadenoma is a benign salivary gland tumor that develops very infrequently. The commonest site for their occurrence is minor salivary glands, where these present as cystic growths with papillary projections. Cystadenomas are often interpreted as mucous
Umber Irshad Butt, Gulfishan Zameer, Aatiqa Rana, Sameer Anjum   +3 more
doaj   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Ligand Activation of the Androgen Receptor Downregulates E-Cadherin-Mediated Cell Adhesion and Promotes Apoptosis of Prostatic Cancer Cells

Neoplasia: An International Journal for Oncology Research, 2003
Androgen independence is the major cause of endocrine therapy failure in advanced prostate cancer (PC). To examine the effects of human androgen receptor (AR) expression on growth of human PC cells, transfection of full-length AR cDNA in an androgen ...
Joanna Nightingale, Khurram S. Chaudhary, Paul D. Abel, Andrew P. Stubbs, Hanna M. Romanska, Stephen E. Mitchell, Gordon W.H. Stamp, El-Nasir Lalani   +7 more
doaj   +1 more source

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera, Agnese Tamanti, Silvia Messina, Nicola Dall'Osto, Teresa Maltempo, Stefano Ziccardi, Matteo Foschi, Maria Grazia Piscaglia, Diana Ferraro, Francesco Crescenzo, Francesca Rossi, Albulena Bajrami, Sabrina Marangoni, Damiano Marastoni, Francesca Benedetta Pizzini, Maria Isabel Leite, Roberta Magliozzi, Patrick Waters, Massimiliano Calabrese, Jacqueline Palace, Ruth Geraldes   +20 more
wiley   +1 more source

Clinicopathological Study of Seronegative Celiac Disease in Adults in Pakistan: A Pilot Study

Middle East Journal of Digestive Diseases, 2017
BACKGROUND Celiac disease (CD) is usually missed, if the serology is negative. We aimed to evaluate the clinicopathological characteristics of seronegative CD (SNCD) and its response to gluten-free diet (GFD) in adult patients.
Farina Mohammad Hanif, Rajesh Kumar Mandhwani, Nasir Hassan Luck, Zaigham Abbas, Muhammed Mubarak, S.Mudassir Laeeq, Abbas Ali Tasneem   +6 more
doaj   +1 more source

SPARC in Breast Carcinomas: A Critical Review

BioMedica, 2020
Breast cancer is the second most common cancer in the world according to World Health Organization statistics. Among Asian countries, Pakistan has the highest incidence of breast cancer. The normal breast development is interplay between various hormones
Waqas Arshad Mughal, Sobia Khalid, Nadia Naseem, AH Nagi   +3 more
doaj   +1 more source

Histopathological Evidence of Neurodegenerative Pathology in Epilepsy: A Systematic Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Epilepsy affects > 50 million people worldwide and is associated with a disproportionate burden of cognitive impairment. Emerging evidence suggests that neurodegenerative proteinopathies, particularly hyperphosphorylated tau (p‐tau) and amyloid‐β (Aβ), may contribute to cognitive dysfunction in people with epilepsy (PWE), even in the absence ...
Syeda Amrah Hashmi, Aleksander Luniewski, Vanessa Smith, Matthew McCord, Jaideep Kapur, Mark Quigg, Catherine Joshua, Ifrah Zawar   +7 more
wiley   +1 more source

Recurrent Urethral Phyllodes Tumour Presenting With Urinary Retention: A Case Report and Literature Review

Case Reports in Urology
We report a rare case of a urethral phyllodes tumour. A 58-year-old male presented with urinary retention requiring catheterisation, preceded by a gradual onset of poor urinary flow.
M. Sharif, B. Lamb, N. Etessami, L. Lazzereschi, A. Freeman, G. Ellis   +5 more
doaj   +1 more source