Results 11 to 20 of about 12,226 (182)

Clinical utility of fungal culture and antifungal susceptibility in cats and dogs with histoplasmosis

Journal of Veterinary Internal Medicine, 2023
Background Culture can be used for diagnosis and antifungal susceptibility testing in animals with fungal infections. Limited information is available regarding the diagnostic performance of culture and the susceptibility patterns of Histoplasma spp ...
Andrew S. Hanzlicek, Kate S. KuKanich, Audrey K. Cook, Steven Hodges, John M. Thomason, Rupika DeSilva, Akhilesh Ramachandran, Michelle M. Durkin   +7 more
doaj   +1 more source

Extracellular superoxide dismutase protects Histoplasma yeast cells from host-derived oxidative stress. [PDF]

PLoS Pathogens, 2012
In order to establish infections within the mammalian host, pathogens must protect themselves against toxic reactive oxygen species produced by phagocytes of the immune system.
Brian H Youseff, Eric D Holbrook, Katherine A Smolnycki, Chad A Rappleye   +3 more
doaj   +1 more source

Metabolism of Gluconeogenic Substrates by an Intracellular Fungal Pathogen Circumvents Nutritional Limitations within Macrophages

mBio, 2020
Microbial pathogens exploit host nutrients to proliferate and cause disease. Intracellular pathogens, particularly those exclusively living in the phagosome such as Histoplasma capsulatum, must adapt and acquire nutrients within the nutrient-limited ...
Qian Shen, Stephanie C. Ray, Heather M. Evans, George S. Deepe, Chad A. Rappleye   +4 more
doaj   +1 more source

Survey of Histoplasma capsulatum in bat guano and status of histoplasmosis in Slovenia, Central Europe

International Journal of Speleology, 2020
There have been increasing reports on the presence of Histoplasma capsulatum in some European countries. The study investigated the presence of Histoplasma in bat guanos, speleologists with records of visiting Histoplasma-endemic regions and patients ...
Janez Mulec, Saša Simčič, Tadeja Kotar, Romina Kofol, Sanja Stopinšek   +4 more
doaj   +1 more source

Diagnosis of Progressive Disseminated Histoplasmosis in Advanced HIV: A Meta-Analysis of Assay Analytical Performance

Journal of Fungi, 2019
Histoplasmosis is an important cause of mortality in people with advanced HIV, especially in countries with limited access to diagnostic assays. Histoplasmosis can be diagnosed using culture, histopathology, and antibody, antigen, and molecular assays ...
Diego H. Caceres, Martha Knuth, Gordana Derado, Mark D. Lindsley   +3 more
doaj   +1 more source

Surface architecture of Histoplasma capsulatum [PDF]

Frontiers in Microbiology, 2011
The dimorphic fungal pathogen Histoplasma capsulatum is the most frequent cause of clinically significant fungal pneumonia in humans. H. capsulatum virulence is achieved, in part, through diverse and dynamic alterations to the fungal cell surface. Surface components associated with H.
Allan J. Guimaraes, Allan J. Guimaraes, Mariana D. de Cerqueira, Joshua D Nosanchuk   +3 more
openaire   +3 more sources

Characterization of patients with clinical diagnosis of Histoplasmosis in the "Hospital Universitario San Ignacio" between 2012-2016

Infectio, 2019
Introduction: Disseminated histoplasmosis is a common presentation in immunosuppressed patients. The introduction of new diagnostic methods and the improvement of the survival of patients with HIV could have changed the clinical characteristics of ...
Isabel Cristina Cuéllar
doaj   +1 more source

Histoplasmosis diseminada progresiva aguda en un paciente inmunocompetente

Medicentro, 2021
La histoplasmosis diseminada progresiva constituye una expresión singular y rara de la infección por Histoplasma capsulatum. Sus formas agudas de presentación suelen aparecer en pacientes con deficiencias inmunitarias graves (fundamentalmente VIH).
Nabil Ghaddar Fuentes, Ana Alicia Vila Toledo, Halbert Hernández Negrín   +2 more
doaj  

The Eng1 β-Glucanase Enhances Histoplasma Virulence by Reducing β-Glucan Exposure

mBio, 2016
The fungal pathogen Histoplasma capsulatum parasitizes host phagocytes. To avoid antimicrobial immune responses, Histoplasma yeasts must minimize their detection by host receptors while simultaneously interacting with the phagocyte.
Andrew L. Garfoot, Qian Shen, Marcel Wüthrich, Bruce S. Klein, Chad A. Rappleye   +4 more
doaj   +1 more source

Cost-effectiveness evaluation of routine histoplasmosis screening among people living with advanced HIV disease in Latin America and the Caribbean.

PLOS Global Public Health, 2023
Histoplasma antigen can be detected in people with advanced HIV disease (AHD), allowing for early and accurate diagnosis of histoplasmosis. The aim of this analysis was to assess the cost-effectiveness of routine histoplasmosis screening using antigen ...
Radha Rajasingham, Narda Medina, Gabriel T Mousquer, Diego H Caceres, Alexander Jordan, Mathieu Nacher, Diego R Falci, Ayanna Sebro, Alessandro C Pasqualotto, Omar Sued, Tom Chiller, Freddy Perez   +11 more
doaj   +1 more source