Canadian Journal of Research, 1948 Tuberculate spores distinguish the mold stage of Histoplasma from that of related pathogenic fungi. The tuberculations are not thickenings of the spore wall. They are extensions of the spore contents through the wall openings. The whole or the tip of a tuberculation may become detached and act as a spore.
Eleanor Silver Dowding
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Extracellular superoxide dismutase protects Histoplasma yeast cells from host-derived oxidative stress. [PDF]
PLoS Pathogens, 2012 In order to establish infections within the mammalian host, pathogens must protect themselves against toxic reactive oxygen species produced by phagocytes of the immune system.
Brian H Youseff +3 more
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Phenotypic characterization of cryptic species in the fungal pathogen Histoplasma
mSphereHistoplasmosis is an endemic mycosis that often presents as a respiratory infection in immunocompromised patients. Hundreds of thousands of new infections are reported annually around the world.
Victoria E. Sepúlveda +4 more
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Histoplasma Responses to Nutritional Immunity Imposed by Macrophage Activation
Journal of Fungi, 2019 The fungal pathogen Histoplasma capsulatum resides within the phagosome of host phagocytic cells. Within this intracellular compartment, Histoplasma yeast replication requires the acquisition of several essential nutrients, including metal ions.
Peter J. Brechting, Chad A. Rappleye
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Surface architecture of Histoplasma capsulatum [PDF]
Frontiers in Microbiology, 2011 The dimorphic fungal pathogen Histoplasma capsulatum is the most frequent cause of clinically significant fungal pneumonia in humans. H. capsulatum virulence is achieved, in part, through diverse and dynamic alterations to the fungal cell surface. Surface components associated with H.
Allan J. Guimaraes +3 more
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Updates in the Language of
mBio, 2018 In a recent article, Sepúlveda et al. (mBio 8:e01339-17, 2017, https://doi.org/10.1128/mBio.01339-17) investigated the genetic structure and evolutionary history of the human pathogen Histoplasma.
Pierre Gladieux
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Genomic epidemiology of Histoplasma in Africa
mBioHistoplasmosis, the disease caused by thermally dimorphic fungi in the genus Histoplasma, is usually associated with pulmonary involvement in healthy individuals and a disseminated syndrome in immunocompromised patients.
Rutendo E. Mapengo +15 more
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Contribuição ao estudo de Histoplasma capsulatum (Darling, 1906) Contribuition to the study of Histoplasma capsulatum, (Darling, 1906) [PDF]
Memorias do Instituto Oswaldo Cruz, 1972 Usando o meio de amônio-sulfato-glicose, conseguimos que oito amostras estéreis de Histoplasma capsulatum voltassem a produzir estalagmosporos.Using the Amonium sulfate glucose medium we succeed in obtaining stalagmospores in eight sterile strains of ...
M. Carlota Pedroso, N. Callado Marçano
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High prevalence and mortality due to Histoplasma capsulatum in the Brazilian Amazon: An autopsy study. [PDF]
PLoS Neglected Tropical Diseases, 2021 BackgroundHistoplasmosis is acquired by inhalation of spores of the dimorphic fungus Histoplasma spp. Although this pathogen is distributed worldwide, it is more prevalent in the Americas.
Natalia Rakislova +23 more
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Granulomatous Hepatitis Secondary to Histoplasma Infection after Treatment with Infliximab [PDF]
Case Reports in Hepatology, 2013 Classical presentation of Histoplasma infection includes fever and respiratory symptoms. Opportunistic microorganisms must be suspected on immunocompromised patients who develop bizarre symptoms.
L. Barrera +4 more
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