Extracellular superoxide dismutase protects Histoplasma yeast cells from host-derived oxidative stress. [PDF]
PLoS Pathogens, 2012 In order to establish infections within the mammalian host, pathogens must protect themselves against toxic reactive oxygen species produced by phagocytes of the immune system.
Brian H Youseff +3 more
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Phenotypic characterization of cryptic species in the fungal pathogen Histoplasma
mSphereHistoplasmosis is an endemic mycosis that often presents as a respiratory infection in immunocompromised patients. Hundreds of thousands of new infections are reported annually around the world.
Victoria E. Sepúlveda +4 more
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Histoplasma Responses to Nutritional Immunity Imposed by Macrophage Activation
Journal of Fungi, 2019 The fungal pathogen Histoplasma capsulatum resides within the phagosome of host phagocytic cells. Within this intracellular compartment, Histoplasma yeast replication requires the acquisition of several essential nutrients, including metal ions.
Peter J. Brechting, Chad A. Rappleye
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Canadian Journal of Research, 1948 Tuberculate spores distinguish the mold stage of Histoplasma from that of related pathogenic fungi. The tuberculations are not thickenings of the spore wall. They are extensions of the spore contents through the wall openings. The whole or the tip of a tuberculation may become detached and act as a spore.
Eleanor Silver Dowding
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Updates in the Language of
mBio, 2018 In a recent article, Sepúlveda et al. (mBio 8:e01339-17, 2017, https://doi.org/10.1128/mBio.01339-17) investigated the genetic structure and evolutionary history of the human pathogen Histoplasma.
Pierre Gladieux
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Contribuição ao estudo de Histoplasma capsulatum (Darling, 1906) Contribuition to the study of Histoplasma capsulatum, (Darling, 1906) [PDF]
Memorias do Instituto Oswaldo Cruz, 1972 Usando o meio de amônio-sulfato-glicose, conseguimos que oito amostras estéreis de Histoplasma capsulatum voltassem a produzir estalagmosporos.Using the Amonium sulfate glucose medium we succeed in obtaining stalagmospores in eight sterile strains of ...
M. Carlota Pedroso, N. Callado Marçano
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Granulomatous Hepatitis Secondary to Histoplasma Infection after Treatment with Infliximab [PDF]
Case Reports in Hepatology, 2013 Classical presentation of Histoplasma infection includes fever and respiratory symptoms. Opportunistic microorganisms must be suspected on immunocompromised patients who develop bizarre symptoms.
L. Barrera +4 more
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Three transporters, including the novel Gai1 permease, drive amino acid uptake in Histoplasma yeasts
VirulenceThe dimorphic fungus Histoplasma capsulatum, which almost exclusively resides within host phagocytic cells during infection, must meet its nutritional needs by scavenging molecules from the phagosome environment.
Stephanie C. Ray +2 more
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Emerging Antifungal Resistance in Tropical Mycoses: A Genomic and Clinical Perspective From Endemic Zones. [PDF]
J R Soc N ZAntifungal resistance in tropical mycoses is an increasingly important component of the global antimicrobial resistance crisis, particularly in endemic regions where diagnostic capacity, therapeutic options, and surveillance systems are limited. This review synthesizes clinical, environmental, and genomic evidence on resistance in major endemic and ...
Miraloglu M.
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High Genetic Diversity of Histoplasma in the Amazon Basin, 2006–2017
Emerging Infectious DiseasesHistoplasmosis is one of the most common pulmonary mycosis diseases in the world. Genome sequencing has revealed that Histoplasma, the cause of histoplasmosis, is composed of several phylogenetic species.
Tani Ly +16 more
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