Results 21 to 30 of about 12,046 (172)

The Eng1 β-Glucanase Enhances Histoplasma Virulence by Reducing β-Glucan Exposure

open access: yesmBio, 2016
The fungal pathogen Histoplasma capsulatum parasitizes host phagocytes. To avoid antimicrobial immune responses, Histoplasma yeasts must minimize their detection by host receptors while simultaneously interacting with the phagocyte.
Andrew L. Garfoot   +4 more
doaj   +1 more source

Cost-effectiveness evaluation of routine histoplasmosis screening among people living with advanced HIV disease in Latin America and the Caribbean.

open access: yesPLOS Global Public Health, 2023
Histoplasma antigen can be detected in people with advanced HIV disease (AHD), allowing for early and accurate diagnosis of histoplasmosis. The aim of this analysis was to assess the cost-effectiveness of routine histoplasmosis screening using antigen ...
Radha Rajasingham   +11 more
doaj   +1 more source

Chromosome-Level Genome Assembly of a Human Fungal Pathogen Reveals Synteny among Geographically Distinct Species

open access: yesmBio, 2022
Histoplasma capsulatum, a dimorphic fungal pathogen, is the most common cause of fungal respiratory infections in immunocompetent hosts. Histoplasma is endemic in the Ohio and Mississippi River Valleys in the United States and is also distributed ...
Mark Voorhies   +10 more
doaj   +1 more source

High prevalence and mortality due to Histoplasma capsulatum in the Brazilian Amazon: An autopsy study.

open access: yesPLoS Neglected Tropical Diseases, 2021
BackgroundHistoplasmosis is acquired by inhalation of spores of the dimorphic fungus Histoplasma spp. Although this pathogen is distributed worldwide, it is more prevalent in the Americas.
Natalia Rakislova   +23 more
doaj   +1 more source

Persistence of histoplasma in adrenals 7 years after antifungal therapy

open access: yesIndian Journal of Endocrinology and Metabolism, 2013
Adrenal histoplasmosis is an uncommon cause for adrenal insufficiency. The duration of treatment for adrenal histoplasmosis is not clear. Existing treatment regimens advocate antifungals given for periods ranging from 6 months to 2 years.
Deepak Kothari   +4 more
doaj   +1 more source

Bilateral adrenal histoplasmosis in a diabetic patient: A case report and review of cases in India

open access: yesApollo Medicine, 2019
Disseminated histoplasmosis usually affects immunocompromised and immunosuppressed individuals and may involve various organ systems of our body. The definitive diagnosis of histoplasmosis is very challenging because it usually presents with nonspecific ...
Hena Butta   +6 more
doaj   +1 more source

The power of many: when genetics met yeasts and high‐throughput

open access: yesBiological Reviews, EarlyView.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Infection control in the brain and the eye

open access: yesActa Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester   +2 more
wiley   +1 more source

An Update on Invasive Fungal Infections in Solid Organ Transplant Recipients

open access: yesTransplant Infectious Disease, EarlyView.
ABSTRACT Invasive fungal infections (IFI) remain a significant infection‐related complication in solid organ transplant recipients (SOTRs), the incidence of which has not changed overtime. With a focus on studies and data published after 2019, this narrative review provides an update on the epidemiology and prevention of IFIs in SOTRs and highlights ...
Tina Marinelli, Shahid Husain
wiley   +1 more source

Prevalence of Histoplasma Antigenuria among Outpatient Cohort with Advanced HIV in Kampala, Uganda

open access: yesJournal of Fungi, 2023
In sub-Saharan Africa, an estimated 25% of people with HIV present with advanced HIV and are at high risk of opportunistic infections. Whereas histoplasmosis has occasionally been seen in Uganda, the understanding of the local risk of acute infection is ...
Preethiya Sekar   +13 more
doaj   +1 more source

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