Results 21 to 30 of about 22,046 (203)

Detection of (1,3)-β-d-Glucan in Cerebrospinal Fluid in Histoplasma Meningitis [PDF]

, 2018
The diagnosis of central nervous system (CNS) histoplasmosis is often difficult. Although cerebrospinal fluid (CSF) (1,3)-β-d-glucan (BDG) is available as a biological marker for the diagnosis of fungal meningitis, there are limited data on its use for ...
Albers, Amanda, Bloch, Karen C., Chow, Felicia C., Davis, Thomas E., Hage, Chadi A., Khairy, Raed N., Myint, Thein, Raymond-Guillen, Luke, Street, Alan C., Wheat, L. Joseph, Woc-Colburn, Laila, Wright, Patty W., Yamamoto, Tomotaka   +12 more
core   +2 more sources

Diagnosis of Progressive Disseminated Histoplasmosis in Advanced HIV: A Meta-Analysis of Assay Analytical Performance

Journal of Fungi, 2019
Histoplasmosis is an important cause of mortality in people with advanced HIV, especially in countries with limited access to diagnostic assays. Histoplasmosis can be diagnosed using culture, histopathology, and antibody, antigen, and molecular assays ...
Diego H. Caceres, Martha Knuth, Gordana Derado, Mark D. Lindsley   +3 more
doaj   +1 more source

Mac1-Dependent Copper Sensing Promotes Histoplasma Adaptation to the Phagosome during Adaptive Immunity

mBio, 2022
Intracellular pathogens residing within macrophage phagosomes are challenged with recognizing the phagosomal environment and appropriately responding to changing host defense strategies imposed in this organelle.
Stephanie C. Ray, Chad A. Rappleye
doaj   +1 more source

Extracellular superoxide dismutase protects Histoplasma yeast cells from host-derived oxidative stress. [PDF]

PLoS Pathogens, 2012
In order to establish infections within the mammalian host, pathogens must protect themselves against toxic reactive oxygen species produced by phagocytes of the immune system.
Brian H Youseff, Eric D Holbrook, Katherine A Smolnycki, Chad A Rappleye   +3 more
doaj   +1 more source

Absent in vitro interaction between chloroquine and antifungals against Aspergillus fumigatus [PDF]

, 2017
This work was supported by Medical Mycology Section, Department of Medical Microbiology, Radboud University Medical Centre, Nijmegen, the Netherlands.
Seyedmousavi, Seyedmojtaba, van der Lee, Henrich, Verweij, Paul, Warris, Adilia   +3 more
core   +1 more source

Comparative Phylogenomics of Pathogenic and Nonpathogenic Species. [PDF]

, 2015
The Ascomycete Onygenales order embraces a diverse group of mammalian pathogens, including the yeast-forming dimorphic fungal pathogens Histoplasma capsulatum, Paracoccidioides spp. and Blastomyces dermatitidis, the dermatophytes Microsporum spp.
Taylor, John W, Whiston, Emily
core   +3 more sources

The Eng1 β-Glucanase Enhances Histoplasma Virulence by Reducing β-Glucan Exposure

mBio, 2016
The fungal pathogen Histoplasma capsulatum parasitizes host phagocytes. To avoid antimicrobial immune responses, Histoplasma yeasts must minimize their detection by host receptors while simultaneously interacting with the phagocyte.
Andrew L. Garfoot, Qian Shen, Marcel Wüthrich, Bruce S. Klein, Chad A. Rappleye   +4 more
doaj   +1 more source

Cost-effectiveness evaluation of routine histoplasmosis screening among people living with advanced HIV disease in Latin America and the Caribbean.

PLOS Global Public Health, 2023
Histoplasma antigen can be detected in people with advanced HIV disease (AHD), allowing for early and accurate diagnosis of histoplasmosis. The aim of this analysis was to assess the cost-effectiveness of routine histoplasmosis screening using antigen ...
Radha Rajasingham, Narda Medina, Gabriel T Mousquer, Diego H Caceres, Alexander Jordan, Mathieu Nacher, Diego R Falci, Ayanna Sebro, Alessandro C Pasqualotto, Omar Sued, Tom Chiller, Freddy Perez   +11 more
doaj   +1 more source

Histoplasmosis diseminada progresiva aguda en un paciente inmunocompetente

Medicentro, 2021
La histoplasmosis diseminada progresiva constituye una expresión singular y rara de la infección por Histoplasma capsulatum. Sus formas agudas de presentación suelen aparecer en pacientes con deficiencias inmunitarias graves (fundamentalmente VIH).
Nabil Ghaddar Fuentes, Ana Alicia Vila Toledo, Halbert Hernández Negrín   +2 more
doaj  

AIDS-defining illnesses at initial diagnosis of HIV in a large Guatemalan cohort [PDF]

, 2017
BackgroundAnecdotal evidence suggests that a high proportion of patients diagnosed with HIV in Guatemala present with AIDS. There remain limited data on the epidemiology of AIDS-defining illnesses (ADIs) in Central America.MethodsWe conducted a ...
Cordon, Andrea Alonzo, Melendez, Johanna, Powderly, William G, Reinhardt, Samuel W, Ross, Ian, Spec, Andrej, Villatoro, Carlos Mejia   +6 more
core   +2 more sources