Results 71 to 80 of about 22,776 (243)

The Significance of Mono‐ and Dual‐Effective Agents in the Development of New Antifungal Strategies

open access: yesChemical Biology &Drug Design, Volume 105, Issue 1, January 2025.
The future of treating challenging fungal infections lies in novel therapies targeting new antifungal targets, overcoming resistance mechanisms, and exploring innovative dual inhibitors. ABSTRACT Invasive fungal infections (IFIs) pose significant challenges in clinical settings, particularly due to their high morbidity and mortality rates.
Cengiz Zobi, Oztekin Algul
wiley   +1 more source

Variabilidade genética de isolados brasileiros de Histoplasma Capsulatum

open access: yesUNINGÁ Review, 2016
O objetivo desse trabalho foi analisar a diversidade genética de isolados de H. capsulatumno Brasil. Foram selecionadas amostras sequenciadas de H.
GERLAN DA ROCHA SANTOS   +3 more
doaj  

Imported Systemic Endemic Mycoses in Spain 1997–2021: An Analysis of a National Hospital Database

open access: yesMycoses, Volume 68, Issue 1, January 2025.
ABSTRACT Background Systemic endemic mycoses are systemic fungal infections typically found in tropical and subtropical regions. Their global incidence is rising, including in nonendemic countries, mainly due to migration and international travel. They are a major cause of morbidity and mortality worldwide, especially in immunocompromised patients ...
Jara Llenas‐García   +3 more
wiley   +1 more source

Updates in the Language of Histoplasma Biodiversity

open access: yesmBio, 2018
In a recent article, Sepúlveda et al. (mBio 8:e01339-17, 2017, https://doi.org/10.1128/mBio.01339-17) investigated the genetic structure and evolutionary history of the human pathogen Histoplasma.
Pierre Gladieux
doaj   +1 more source

Severe Pulmonary Blastomycosis in a Young Adult: Probable Role of E‐Cigarette Use in Immunosuppression

open access: yesCase Reports in Medicine, Volume 2025, Issue 1, 2025.
Background: E‐cigarette use has become increasingly prevalent among young adults, raising concerns about its potential health impact and susceptibility to infections. Blastomyces dematitidis, the causative agent of blastomycosis, is a dimorphic fungus endemic to certain regions of the United States.
Rajat Gupta   +7 more
wiley   +1 more source

Challenging granulomatous differential diagnosis of CNS lesions in a 75-year-old patient with indolent lymphoma

open access: yesFrontiers in Immunology
We report here on a patient with concomitant indolent lymphoma who showed a rapid progressive deterioration of his general condition and emerging neurological symptoms.
Lorenz Thurner   +12 more
doaj   +1 more source

HISTOPLASMIN SURVEY IN HIV-POSITIVE PATIENTS: RESULTS FROM AN ENDEMIC AREA IN NORTHEASTERN BRAZIL

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2013
SUMMARY Background. Disseminated histoplasmosis is common in AIDS patients with advanced immunosuppression in Ceará, Northeastern Brazil. The goal of this study was to determine the prevalence of Histoplasma infection in patients with HIV ...
Fabricia Salvador Bezerra   +8 more
doaj   +1 more source

Antibody Therapy for Histoplasmosis [PDF]

open access: yes, 2012
The endemic human pathogenic fungus Histoplasma capsulatum is a major fungal pathogen with a broad variety of clinical presentations, ranging from mild, focal pulmonary disease to life-threatening systemic infections.
Guimarães, Allan J.   +3 more
core   +3 more sources

Multiple keratotic papulonodular lesions in a human immunodeficiency virus‐negative patient

open access: yes
JEADV Clinical Practice, Volume 4, Issue 1, Page 359-363, March 2025.
Rawan Almutairi   +4 more
wiley   +1 more source

Histoplasma Capsulatum: Mechanisms for Pathogenesis [PDF]

open access: yes, 2018
Histoplasmosis, caused by the dimorphic environmental fungus Histoplasma capsulatum, is a major mycosis on the global stage. Acquisition of the fungus by mammalian hosts can be clinically silent or it can lead to life-threatening systemic disease, which can occur in immunologically intact or deficient hosts, albeit severe disease is more likely in the ...
Maria G. Ponce   +3 more
openaire   +3 more sources

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