Results 111 to 120 of about 1,526,402 (238)
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Instrument or object? The New Zealand piano on display [PDF]
, 2011 The piano is rather a unique display item in the museum or the historic house. Firstly, whether an upright or a grand, the piano is an imposing, substantial object that occupies significant space within a setting and immediately demands attention because
Moffat, Kirstine
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Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
BuildingsThe process of urbanization has accelerated economic growth while also presenting social challenges. Urban renewal is crucial for achieving sustainable urban development, especially by preserving traditional villages as cultural heritage sites within ...
Jun Xia +4 more
doaj +1 more source
The Digital Atlas of Ancient Rare Diseases (DAARD) and its relevance for current research
Orphanet Journal of Rare DiseasesBackground The history of rare diseases is largely unknown. Research on this topic has focused on individual cases of prominent (historical) individuals and artistic (e.g., iconographic) representations.
J. Gresky +9 more
semanticscholar +1 more source
An investigation into practices, issues and improvement opportunities of logistical outsourcing : a study of integrated warehouse services : a thesis presented in partial fulfilment of the requirements for the degree of Master of Applied Science in Logistics and Supply Chain Management at Massey University [PDF]
, 2008 Some Bahasa Indonesian LanguageA pressure to maintain company's profitability and at the same time a need for the company to increase service level and productivity, has forced the organisation to re-engineer its business systems into a more efficient ...
Rachmayani, Novianti
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Cancer ReportsBackground Supposed ‘spontaneous’ remissions in chronic lymphocytic leukaemia (CLL) are extremely rare. By the most stringent immunophenotypic criteria, there are only seven cases to date of unexplained, immune system effected cures. A historic review of
Carmen Wheatley
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Retooling Waterfront Governance in the New York-New Jersey Harbor: Case Studies from Waterfront Cities [PDF]
, 2013 Who is in charge of the waterfront? Everybody and nobody. The scramble of commissions and task forces in the wake of Superstorm Sandy brought the challenge of waterfront governance into sharp relief.
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