Results 101 to 110 of about 31,953 (306)

Urban regeneration of industrial heritage cities: A comparative study of textile manufacturing in Łódź (Poland) and Yazd (Iran)

European Spatial Research and Policy
This study conducts a comparative analysis of the urban regeneration processes in Łódź, Poland, and Yazd, Iran. Despite the fact that both cities share a common historical background in textile manufacturing, they are characterised by distinct political,
Mohammadhossein Dehghan Pour Farashah
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Faunistic researches on spiders (Araneae) in Poland: a historical background and perspectives

, 2023
Faunistic researches on spiders (Araneae) in Poland: a historical background and perspectives.This paper presents the history of research and summarizes the faunistic data on spiders occurring inPoland. An analysis of the degree of knowledge of the national fauna was also carried out.
openaire   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Research trends on traditional Chinese medicine and acute pancreatitis: A bibliometric analysis from 2007 to mid-2023

Heliyon
Background Traditional Chinese Medicine (TCM) is a unique medical system of historic significance, holding substantial influence within China and beyond. In recent years, the efficacy of TCM in treating acute pancreatitis has been substantiated.
Wang-peng Lan, Wen Guo, Xin Zhou, Zhi Li
semanticscholar   +1 more source

Sustainability of Buildings in Historic City of Malacca

, 2018
The paper discusses the sustainability of the buildings on the western side of the Historic City of Malacca with the help of the implementation of conservation policies.
W. Ismail
semanticscholar   +1 more source

Più unica che rara: la genealogia della Vergine a sud delle Alpi. Tradizioni, committenze e canali di circolazione di un'insolita iconografia

Intrecci d'arte, 2015
The iconographic research deals with the particular topic of the Holy Kinship, a common subject in the north of the Alps, but almost absent in Italy.
Valeria Butera
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Development of a Blockchain-Based Platform to Enable Indigenous Data Sovereignty and Shared Research Participation With Indigenous Communities: Technology Prototyping and Community Engagement Study

Journal of Medical Internet Research
Background Historic and ongoing problematic practices regarding the collection, storage, and use of Indigenous health data have led to the need to ensure principles of Indigenous Data Sovereignty (IDS) are followed in research practices and technology ...
T. Mackey, Alec J. Calac, Tiana J McMann, Ken Miyachi, Samantha Hurst, Keolu Fox, Burt Dillabaugh, Kelle Dhein, Guthrie Ducheneaux, Joseph M. Yracheta   +9 more
semanticscholar   +1 more source