Results 111 to 120 of about 482,315 (310)
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
A Visual Analysis and Review of Chinese Qilou Architectural Heritage Based on CiteSpace
Chinese Qilou Architecture Heritage (CQAH) serves commercial and residential functions, integrates Southeast Asian and local Chinese architectural features, and is a unique testimony to modern commerce and culture of the overseas Chinese hometown.
Yilin Wu +3 more
doaj +1 more source
Methods of Nature: Landscapes from the Gettysburg College Collection
Methods of Nature: Landscapes from the Gettysburg College Collection is the third annual exhibition curated by students enrolled in the Art History Methods course.
Chason, Molly A. +5 more
core
Recovering a Lost Story Using Oral History: The United States Supreme Court\u27s Historic Green v. New Kent County, Virginia, Decision [PDF]
In 1965, New Kent County, located just east of Richmond, Virginia, became the setting for the one of the most important school desegregation cases since Brown v. Board of Education. Ten years after the U.S.
Allen, Jody L., Daugherity, Brian J.
core +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Background Over the past 4 decades, time depth recorders (TDRs) have become an essential tool for research into the previously unexplored diving behavior of marine organisms.
EmmaLi G. Tsai +3 more
doaj +1 more source
The Functional Transformation Buildings in The Old City Semarang Based on The Urban Sustainable-Conservation Concepts [PDF]
Conservation and Sustainability are inspiring the region of the Old City in Semarang. As the meanings of both words, the aim of conservation and sustainability in this region is addressed to secure long-term harmony between man and nature, to achieve ...
Setyowati, Erni
core
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source

