Results 41 to 50 of about 482,315 (310)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Non Algebraic Techniques for Digital Processing of Historic Painting Research Documentation
Digital Presentation and Preservation of Cultural and Scientific Heritage, 2018 Conservation of historic painting requires comprehensive and correct information to be analyzed during the diagnostic and decision making process in a systematic and rational approach.
Magdelena Stoyanova +2 more
doaj +1 more source
Jurnal Historica, 2023 This article contains the history of the establishment of the Sarekat Islam building, including the background to the establishment of the building, its functions, and its development over time.
Siti Khusnul Khotimah
doaj +1 more source
The Eurovision St Andrews collection of photographs [PDF]
, 2006 This report describes the Eurovision image collection compiled for the ImageCLEF (Cross Language Evaluation Forum) evaluation exercise. The image collection consists of around 30,000 photographs from the collection provided by the University of St ...
Clough P. +6 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Kajian Linguistik dan Sastra, 2013 BSTRACT In 404 Hijri / 1014 C, Andalusia of Cordoba su ered chaotic situations not only in politics but also in other segments of life, especially in sex. Free sex ourished and remained arguable.
Eva Farhah +3 more
doaj +1 more source
Rigidity in Personality Organization: The Historical Background and Research Issue
Психология. Журнал Высшей школы экономики, 2023 The –issues of research on rigidity in personality organization – are discussed indepth in this article as the main theoretical and applied aspects of one of the relevant areas of general psychology. In this regard, the reasons for the formulation of the stated problem in its proper psychological aspect are presented and interpreted: the absence of a ...
openaire +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Geodesy and Cartography, 2012 This paper researches the representation of Lithuanian railways as a geographical object on old maps. It highlights the most significant stages of development of wide and narrow gauge railways and that of cartography in the background of historical ...
Viktoras Lukoševičius
doaj +1 more source