PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
C & E Thayer Bank, Tillamook, Oregon, date unknown
C & E Thayer Bank, Tillamook, Oregon, date unknown. The bank was owned and operated by Claudius and Estelle Bush Thayer. Estelle Bush Thayer was the daughter of Asahel Bush II who built Bush House.
unknown
core
Mining the past for the future: cyanobacterial herbarium specimens for systematics, evolution, and cyanotoxin diversity. [PDF]
Dvořák P, Casamatta DA.
europepmc +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Longitudinal Antimicrobial Susceptibility Shifts in Environmental <i>Legionella pneumophila</i> from a Drinking Water Distribution System. [PDF]
Madagi L +4 more
europepmc +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Historic conservatory and herb garden in Bush's Pasture Park in Salem, Oregon
This photo was displayed as a part of the Gardens of Bush's Pasture Park Exhibit from April through June 1996 in the Heritage Room at the Salem Public Library.
unknown
core
Using pedigree tracking of the ex situ metacollection of Amorphophallus titanum (Araceae) to identify challenges to maintaining genetic diversity in the botanical community. [PDF]
Murrell OG +7 more
europepmc +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Bycatch in a bottle: what taxa are recoverable from metabarcoding DNA in historical invertebrate collection preservative fluid? [PDF]
Seresinghe A +10 more
europepmc +1 more source

