Results 141 to 150 of about 9,878,707 (244)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Historic marker for E. Lorne Knight in Yamhill County, Oregon

, 1940
This photo is of a bronze historic marker mounted in a rock in Yamhill County, Oregon. It says: ""In Memory of E. Lorne Knight 1893-1923, Member of Stefansson Canadian Arctic Expedition 1915-1919, Reached 89 degrees 20 minutes North Latitude.
Stryker, Hugh
core  

Governance models for cultural assets owned by public healthcare organizations: Italian and Portuguese experiences. [PDF]

Front Public Health
Persiani N, Landini G, José H.
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

History of Medicine Library at the Royal Australasian College of Physicians is alive and well and thriving in the digital age. [PDF]

Intern Med J
Storey CE.
europepmc   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Oregon Historic Trails Advisory Council ... annual report

, 2004
Oregon Historic Trails Advisory Council.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

Exploring the Quality of Historic DNA From Pinned Beetles. [PDF]

Ecol Evol
Lukic D, Petersen M, Patel J, Krovi RS, Ahrens D, Gerstmeier R, Eberle J.   +6 more
europepmc   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Museum specimens reveal the genomic consequences of long-term population decline in an insect pollinator. [PDF]

Mol Biol Evol
Mullin VE, Merchant HN, Arce AN, Nash W, Notton DG, Whiffin A, Blagoderov V, Broad GR, Hogan J, Hunter T, Jackson S, Judd S, Ollerton J, Brace S, Gill RJ, Barnes I.   +15 more
europepmc   +1 more source