Results 41 to 50 of about 29,592 (247)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The International Council on Monuments and Sites (ICOMOS) Florence Charter 1981 on Historic Gardens sets the first guidelines for the definition of a historic garden, in which sites such as large parks, whether formal or landscape, are included.
Eleni Athanasiadou
doaj +1 more source
THE CHT2 PROJECT: DIACHRONIC 3D RECONSTRUCTION OF HISTORIC SITES [PDF]
Digital modelling archaeological and architectural monuments in their current state and in their presumed past aspect has been recognized not only as a way for explaining to the public the genesis of a historical site, but also as an effective tool for ...
G. Guidi +3 more
doaj +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
This article explores the relations between the provisions of the Act on the Protection and Guardianship of Monuments and Sites and the Construction Law from the perspective of modern historic preservation.
Helena Jadwiszczok-Molencka
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Eksistensi Bangunan dan Kawasan Bersejarah di Kota Manado dan Peranannya sebagai Urban Heritage
The development of Manado City reflects modern life in urban areas, particularly population growth, massive development and the dynamics of various activities. These qualities bring changes in the use of space in urban environmental functions and changes
Cynthia E.V Wuisang +2 more
doaj +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
PRACE KONSERWATORSKIE, A KLASYFIKACJA ZABYTKÓW
Value assessment of historic monuments and sites and their classification are affected by conservation works and the impact they exert on elements of historical significance.
Małgorzata Korpała
doaj +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source

