Results 61 to 70 of about 55,359 (280)
O POCZĄTKACH KLASYFIKACJI ZABYTKÓW.O WADACH I ZALETACH POLSKICH SYSTEMÓW WARTOŚCIOWANIA ZABYTKÓW
Ochrona Dziedzictwa Kulturowego, 2016 This article discusses practices of classification of historic monuments and sites which have been adopted in Poland so far. The author of this article presents criteria pertaining to categorising and making inventory of historic monuments and sites ...
Jakub Lewicki
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Situating Place and Wellbeing Within Heritage Interactions for Older Adults
HeritageAs the global population ages, more older adults are engaging with the historic environment than ever before. However, the needs of this population may not always be met by local and national heritage sites and organizations.
Jessica Bowden +2 more
doaj +1 more source
Determinants of Historic and Cultural Landmark Designation: Why We Preserve What We Preserve [PDF]
There is much interest among cultural economists in assessing the effects of heritage preservation policies. There has been less interest in modeling the policy choices made in historic and cultural landmark preservation.
Krupka, Douglas J., Noonan, Douglas S.
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Molecular Oncology, Volume 20, Issue 6, Page 1513-1534, June 2026.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Draft Genomes Sequences of 11 Geodermatophilaceae Strains Isolated from Building Stones from New England and Indian Stone Ruins found at historic sites in Tamil Nadu, India. [PDF]
J Genomics, 2022 Ennis NJ +7 more
europepmc +1 more source
Molecular Oncology, Volume 20, Issue 6, Page 1535-1555, June 2026.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
, 1960 Article includes a preliminary report by the Oklahoma Historic Sites Committee of the OHS about the inscriptions found along the Santa Fe Trail.
Oklahoma Historic Sites Committee
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Molecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source