Results 41 to 50 of about 55,359 (280)
Guidelines for On-Site Assessment of Historic Timber Structures [PDF]
International Journal of Architectural Heritage, 2014 In the scope of European Cooperation in Science and Technology-Wood Science for Conservation of Cultural Heritage (COST IE0601-WoodCultHer) (available at http://www.woodculther.org) it was agreed to produce Guidelines for the Assessment of Historic Timber Structures, covering the principles and possible approaches for the safety assessment of old ...
Cruz H +7 more
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
KWALIFIKACJA WARTOŚCI ZABYTKU W ŚWIETLE PRAWA STANÓW ZJEDNOCZONYCH AMERYKI PÓŁNOCNEJ
Ochrona Dziedzictwa Kulturowego, 2016 This article examines value-based selection criteria applied in classification of historic monuments and sites in American legislation. Furthermore, the author of this article arrives at conclusions which could be applied in the Polish provisions of law.
Wojciech Kowalski
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Urban, Planning and Transport ResearchThe literature on city branding has two main shortcomings. First, each related factor is evaluated individually, resulting in an insufficiently comprehensive evaluation.
Takumi Kato +2 more
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ON THE HISTORICAL DEVELOPMENT OF TOURIST SITES
Bulletin of Kazakh Leading Academy of Architecture and Construction, 2023 The article examines the development of trade and economic relations of early and medieval states, the development and formation of tourism, examines architectural monuments, which performed different functions, while continuing to be relevant to the present day, in modern conditions.
I.I. Ostapenko +2 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Heritage, 2019 The International Council on Monuments and Sites (ICOMOS) Florence Charter 1981 on Historic Gardens sets the first guidelines for the definition of a historic garden, in which sites such as large parks, whether formal or landscape, are included.
Eleni Athanasiadou
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Ochrona Dziedzictwa Kulturowego, 2016 This article explores the relations between the provisions of the Act on the Protection and Guardianship of Monuments and Sites and the Construction Law from the perspective of modern historic preservation.
Helena Jadwiszczok-Molencka
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