Results 71 to 80 of about 248,895 (305)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Improving the Energy Efficiency, Limiting Costs and Reducing CO₂ Emissions of a Museum Using Geothermal Energy and Energy Management Policies

Energies, 2019
Museums are major energy consumers amongst buildings, especially if they are housed in historical constructions. Museums usually present high energy demand for the air-conditioning due to their architectonical and structural characteristics, such as the ...
Gianluca Cadelano, Francesco Cicolin, Giuseppe Emmi, Giulia Mezzasalma, Davide Poletto, Antonio Galgaro, Adriana Bernardi   +6 more
doaj   +1 more source

Vermont Building

, 1908
Image shows the Richards Street facade of the Vermont Building, while under ...
Shipler Commercial Photographers, Shipler Commercial Photographers; Shipler, Harry   +1 more
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Templeton Building

In the 1880\u27s, the Daniel H. Wells home was torn down to make way for the Templeton Building (completed in 1890) at the intersection of Main Street and South Temple.

core   +7 more sources

Valorisation of Tuff and Brick Wastes by Alkali Activation for Historical Building Remediation. [PDF]

Materials (Basel), 2023
Capasso I, D'Angelo G, Fumo M, Del Rio Merino M, Caputo D, Liguori B.   +5 more
europepmc   +1 more source

Building roads and trails in British Columbia

, 1995
Audio recording of author Robert G. Harvey's presentation to the Nanaimo Historical Society about building roads and trails in British Columbia.https://library.viu.ca/libinfo ...
Harvey, Robert G.
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Mardin Eski Hükümet Konağının Dünü ve Bugününe Dair Gözlemler

International Journal of Mardin Studies (IJMS), 2023
Tarihî yapılar tarihsel süreç içerisinde birçok bozulmayla karşı karşıya kalmaktadır. Bu yapılar, eski veya yeni işlevleri aracılığıyla tekrardan yaşanabilir hale getirilebilmektedir. Böylece yapının ayakta kalması, zamana karşı direnmesi ve daha görünür
Rojat Aksoy Işık
doaj  

Guaranty Building, 2008

, 2000
Guaranty Building, 2008.Appears in Destination Indiana 3Destination Indiana A New Look for the ...
Indiana Historical Society
core