Results 91 to 100 of about 700,835 (290)
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
The Situation Development of Timor Leste Refugees Post Election From The Social and Legal Aspect [PDF]
, 2012 As neighbouring countries not only based upon its geographical but also its historical, Indonesia and Timor Leste has developed a lot of effort to overcome residual issues that arose from Timor Leste separation from Indonesia such as the refugee problem.
Krustiyati, J.M. Atik
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The first Othman Constitution and the possibility of promotion of Othman community in view of Jalal Nuri [PDF]
تاریخ اسلام, 2013 The writing of the first constitution in 1875 (A. D) and 1293 (After Hijrah) led to different arguments and suggestions, and then this issue was followed by the attraction of attention of scholars and researchers.
Qolam Ali Pashazadeh
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The Constitutional Referendum in Historical Perspective
, 2019 Government
Zachary Elkins, Alexander Hudson
openaire +3 more sources
LEGAL OBLIGATION IN THE CONSTITUTION
Вестник Кемеровского государственного университета, 2015 This study examines legal responsibilities in the constitution. Legal obligation is the key category of any branch of law. Legal duties of constitutional nature are of particular socio-legal significance, given the fundamental nature of the provisions of
V. P. Shchennikov, N. V. Antsiferov
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Probing Questions for a Forward-Looking People
, 1987 At the risk of oversimplifying recent Quaker developments in America, we could consider the 1950s a decade of rediscovery and redefinition among Friends.
Anderson, Paul
core