Results 111 to 120 of about 43,776 (307)

Constitution as a legal instrument of society: issues and trends

open access: yesRUDN Journal of Law, 2015
In the article there is an attempt to understand, taking into account the historical experience, the social, legal and economic nature of the Constitution as a legal management tool, issued in the end of the XVIII century, which has a dual nature. On the
L YU Grudtsina, A V Lagutkin
doaj  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Utah, State Constitution P.3

open access: yes, 1969
Constitution of the State of Utah, page 5, 1969 ...

core  

Notes and Documents [PDF]

open access: yes, 1933
Notes and Documents section for Volume 11, Number 3, September 1933. It includes a proposed amendment to the Oklahoma Historical Society's constitution and the minutes for the quarterly meeting of the society's Board of Directors held on July 27 ...
Oklahoma Historical Society
core  

Penerapan Syariat Islam terhadap Peraturan Daerah dalam Sistem Hukum Nasional Indonesi

open access: yesHunafa: Jurnal Studia Islamika, 2015
The application of sharia in Indonesia has a strong historical roots, even predates the history of European law itself. So if there is a desire of some parties to implement it, it is not something fabricated or new demands are groundless,but already has ...
Nur Rohim Yunus
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Constitution Building p.5

open access: yes
Constitution ...
McNeely, L. V.
core  

Kansas State Historical Society News Releases, 2006

open access: yes, 2006
This internet resource contains news releases issued throughout the yearKansas Museum Of History Receives museum Accreditation Survivor Winner Celebrates Kansas Day At The Capitol Dinosaur Eggs From China On Exhibit At Museum Capitol Kansas Day ...
Kansas State Historical Society
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

GREGORY LEYH’S APPROACH TO CONSTITUTIONAL HERMENEUTICS: A CRITICAL ANALYSIS OF LEGAL HERMENEUTICS ACCORDING TO HANS-GEORG GADAMER

open access: yesMasalah-Masalah Hukum
Constitutional interpretation is a crucial and evolving field that extends beyond judges, involving legal scholars, citizens, and political theorists. It encompasses various methods such as originalism, textualism, moral reasoning, structural reasoning ...
Muhammad Ilham Hermawan
doaj   +1 more source

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