Results 91 to 100 of about 4,549,446 (295)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

U.S. Frigate Constitution

open access: yes, 1931
The U.S. Frigate Constitution (also known as the USS Constitution), a U.S. Navy frigate that was commissioned as part of the Naval Act of 1794 and is the oldest still afloat. In 1931, the Constitution began a tour of 90 U.S.

core   +2 more sources

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Report of the Kansas Joint Commission on Constitution Revision [1961]

open access: yes, 1961
Submitted to the Governor and the Legislature of the State of Kansas ; prepared by Walter E. Sandelius, chairman January 16, 1961.Kansas Joint Commission on Constitution Revision -- Member Appointed By The Governor -- Members Appointed By The Kansas ...
Kansas Commission on Constitution Revision
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

LEGAL OBLIGATION IN THE CONSTITUTION

open access: yesВестник Кемеровского государственного университета, 2015
This study examines legal responsibilities in the constitution. Legal obligation is the key category of any branch of law. Legal duties of constitutional nature are of particular socio-legal significance, given the fundamental nature of the provisions of
V. P. Shchennikov, N. V. Antsiferov
doaj  

Indiana Historical Society Constitution

open access: yes
Those signing the constitution for the IHS included such notable local citizens as Calvin Fletcher, William Conner, John Tipton, David Wallace, Noah Noble, and John DePauw.
Indiana Historical Society
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

The first Othman Constitution and the possibility of promotion of Othman community in view of Jalal Nuri [PDF]

open access: yesتاریخ اسلام, 2013
The writing of the first constitution in 1875 (A. D) and 1293 (After Hijrah) led to different arguments and suggestions, and then this issue was followed by the attraction of  attention of scholars and researchers.
Qolam Ali Pashazadeh
doaj  

Kansas State Historical Society Annual Report, 2014

open access: yes, 2014
Covers Fiscal Year 2014 The Kansas State Historical Society, Inc., doing business as the Kansas Historical Foundation, is an IRS determined 501(c)(3) non-profit and serves as the fund raising, fund management, membership, and retail organization for the ...
Kansas State Historical Society
core  

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