Results 31 to 40 of about 4,499,602 (300)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

The Dis/Continuity of the Chain: The Negative Dialectic of Tabula Rasa and Palimpsest in Urban Design

Urban Science
Rapid and large-scale urban transformations destabilize historical continuity in both the material fabric of cities and the theoretical assumptions guiding urban design.
Hisham Abusaada, Abeer Elshater
doaj   +1 more source

IMAGINING CHUVASH HISTORICAL TIME: HISTORICAL CONTINUITIES AND INTELLECTUAL FAILURES

Tractus Aevorum, 2017
The concept of historical time is a focal point in the imagination and invention of national history. Among nations without a tradition of independent statehood, historical time was actualized when these nations became independent actors in historical processes.
openaire   +2 more sources

ContinuITy-Project/ContinuITy: Release at project end (v2.9.346)

, 2020
ContinuITy is a research project on "Automated Performance Testing in Continuous Software Engineering", launched by Novatec Consulting GmbH and the University of Stuttgart (Software Quality and Architecture Group).
Tobias Angerstein, Alper Hidiroglu, Henning Schulz, Manuel Palenga   +3 more
core   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

TEXT OF POLICY IN THE BACKGROUND OF CIVILIZATIONAL CONTEXTS AND SUBTEXTS AS A MISSING ELEMENT OF EDUCATIONAL DISCOURSE

Освітній дискурс, 2020
Politics feels the steady influence of the civilization factor first of all and mainly because for various reasons the way of its existence prevents the careful selection of optimal articulation, argumentation and rhetorical approaches; instead of this ...
Zoreslav Samchuk
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Kansas State Historical Society Annual Report, 2015

, 2015
The Kansas State Historical Society, Inc., doing business as the Kansas Historical Foundation, is an IRS determined 501(c)(3) non-profit and serves as the fund raising, fund management, membership, and retail organization for the Kansas Historical ...
Kansas State Historical Society
core   +1 more source