Results 121 to 130 of about 6,086,370 (315)

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Roman Rosdolsky (1898-1967): um intelectual em tempos de extremos

Nova Economia, 2009
This article presents the intellectual trajectory of Roman Rosdolsky, highlighting his contributions to the interpretation of Marx’s works and to the historical studies.
João Antonio de Paula
doaj  

The Southwestern Historical Quarterly, Volume 45, Number 4, April 1942

, 1942
The Texas State Historical Association Quarterly Report includes "Papers read at the meetings of the Association, and such other contributions as may be accepted by the Committee" (volume 1, number 1).
Texas State Historical Association, Webb, Walter P.   +1 more
core  

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Who Founded Ogbomoso? A Reevaluation of the Founding Origin of a City-State

Yoruba Studies Review
Ogbomoso, a 17th-century Yoruba city-state in Nigeria, holds significant cultural and historical value. This study reevaluates its founding origins, challenging narratives centered on Soun Ogunlola. By integrating oral traditions and scholarly analyses,
David Victor Ogunkan
doaj   +1 more source

The Southwestern Historical Quarterly, Volume 52, Number 4, April 1949

, 1949
The Texas State Historical Association Quarterly Report includes "Papers read at the meetings of the Association, and such other contributions as may be accepted by the Committee" (volume 1, number 1).
Texas State Historical Association, Carroll, H. Bailey   +1 more
core  

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Professor Wadia’s contributions to neurology and spinocerebellar ataxia type 2

Arquivos de Neuro-Psiquiatria
The authors present a historical review of the seminal contributions of Professor N. H. Wadia (1925-2016) to neurology, in particular, the first description of spinocerebellar ataxia type 2.
Fernando Spina Tensini, José Luiz Pedroso, Orlando G.P. Barsottini, Hélio A. G. Teive   +3 more
doaj   +1 more source

Southwestern Historical Quarterly, Volume 88, Number 4, April 1985

, 1984
The Texas State Historical Association Quarterly Report includes "Papers read at the meetings of the Association, and such other contributions as may be accepted by the Committee" (volume 1, number 1).
Texas State Historical Association, Ellis, L. Tuffly   +1 more
core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source