Results 111 to 120 of about 1,594,782 (294)

Reconstructing Intellectual Networks

open access: yesDigital Humanities in the Nordic and Baltic Countries Publications, 2019
This paper demonstrates the use of the ESTC as a representation of material history through the extraction and parsing of its data in a way which allows it to be used in social network analysis. In doing this it makes two contributions.
Mark J. Hill   +4 more
doaj   +1 more source

A coral reef as an analogical model to promote collaborative learning on cultural and ethnic diversity in science [PDF]

open access: yes, 2008
An exercise designed to engage students in critical thinking and active conversation about gender, diversity, and ethnicity in science is described.
Gonzalez, Edward L. F., Yost, Robert W.
core  

Nationalism and internationalism in science: the case of the discovery of cosmic rays

open access: yes, 2010
The discovery of cosmic rays, a milestone in science, comprised scientists in Europe and the US and took place during a period characterised by nationalism and lack of communication.
Carlson, Per, De Angelis, Alessandro
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Chinese Historical Institutions and their Contribution for Global Governance

open access: yesDesafíos, 2020
This article makes an interpretation, from a historical institutional perspective, of the idea of Chinese wisdom and solutions for global governance introduced in the recent Chinese official discourse. Its main objective is to shed some light on the strength of the cultural values of China’s historical institutions to negotiate the universalization of ...
openaire   +4 more sources

Legal Form, Commodities and Reproduction: Reading Pashukanis [PDF]

open access: yes, 2013
This chapter offers a feminist reading of Pashukanis’s legal theory as a contribution to critical evaluation of the relationship between legality, commodification and gender. Contemporary feminist interests in the relationship between legal and non-legal
FLETCHER, R
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Brief Overview of the Life and Work of Lyon Henry Appleby, M.D. (1895-1970). [PDF]

open access: yes, 2016
The life and work of Dr. Lyon Henry Appleby, M.D., portrays the essence of a devoted clinician committed to scholarly excellence. Born in Deseronto, Ontario, in 1895 and passing in 1970, Dr.
Cowan, Scott W.   +3 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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