Results 171 to 180 of about 277,480 (307)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

An evaluation scale for the cultural value of heritage buildings. [PDF]

open access: yesPLoS One
Huang H   +3 more
europepmc   +1 more source

Administrative Files - Conferences and Events - Visual Culture and Archives Symposium - April 05, 2013 - Part 18 - Tribute to Francis X. Blouin - Hank Meijer

open access: yes, 2013
Hank Meijer (CEO, Meijer Stores and author) pays tribute to Francis Blouin and the Bentley Historical Libraryhttp://deepblue.lib.umich.edu/bitstream/2027.42/97415/1/040513_18_Meijer ...
Meijer, Hank, Bentley Historical Library
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

The Proceedings of the South Carolina Historical Association

open access: yes, 1983
Annually, the association publishes a journal, The Proceedings, which consists of papers presented at the annual meeting. Agrarian Reform versus Bourbon Democracy: The South Carolina Gubernatorial Campaign of 1890 by Diane Neal John G.
South Carolina Historical Association
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Genetic diversity of horses of the Sargarinsko-Alexeevskaya and Irmen cultures of the Ob-Irtysh region of Western Siberia and their genetic proximity to modern horses of indigenous breeds. [PDF]

open access: yesVavilovskii Zhurnal Genet Selektsii
Kusliy MА   +12 more
europepmc   +1 more source

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