Results 181 to 190 of about 277,480 (307)

Administrative Files - Conferences and Events - Visual Culture and Archives Symposium - April 05, 2013 - Part 14 - "Final Remarks"

open access: yes, 2013
Francis Blouin (Director of the Bentley Historical Library and Professor of History and Information at the University of Michigan) provides final remarks for the symposium and reflects upon the issues and considerations raised by speakershttp://deepblue ...
Blouin, Francis   +1 more
core  

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Replication Efficiency of Contemporary Highly Pathogenic Avian Influenza A(H5N1) Virus Isolates in Human Nasal Epithelium Model. [PDF]

open access: yesEmerg Infect Dis
Flagg M   +6 more
europepmc   +1 more source

Administrative Files - Conferences and Events - Visual Culture and Archives Symposium - April 05, 2013 - Part 17 - Tribute to Francis X. Blouin - Angela Dillard

open access: yes, 2013
Angela Dillard (Director of Residential College and Professor in the Department of Afroamerican & African Studies) discusses her experience conducting research at the Bentley Historical Libraryhttp://deepblue.lib.umich.edu/bitstream/2027.42/97414/1 ...
Dillard, Angela   +1 more
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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