Results 211 to 220 of about 7,320 (297)

Impact of Nitrogen Deposition on Carbon and Nitrogen Cycling in Peatlands Under Land‐Use Change

Land Degradation &Development, EarlyView.
ABSTRACT Increasing nitrogen (N) deposition significantly alters carbon and N dynamics in peatlands by affecting microbial processes, enhancing greenhouse gas emissions and nutrient leaching into adjacent waters. However, how peatland conversion for agriculture and forestry influences the fate of added N under elevated atmospheric deposition remains ...
Yujing Deng, Kyle S. Boodoo, Klaus‐Holger Knorr, Stephan Glatzel   +3 more
wiley   +1 more source

First 20 Years of Orbitrap Mass Spectrometry as the Mainstream Analytical Technique

Mass Spectrometry Reviews, EarlyView.
ABSTRACT This review traces the first 20 years of Orbitrap mass spectrometry as a mainstream high‑resolution and accurate‑mass (HR/AM) technology. It outlines the historical development of the Orbitrap analyzer, the evolution of major instrument families, and the key technological innovations that enabled its widespread adoption. Particular emphasis is
Alexander Makarov
wiley   +1 more source

Trastuzumab deruxtecan in HER2-low metastatic breast cancer: long-term survival analysis of the randomized, phase 3 DESTINY-Breast04 trial. [PDF]

Nat Med
Modi S, Jacot W, Iwata H, Park YH, Vidal Losada M, Li W, Tsurutani J, Ueno NT, Zaman K, Prat A, Papazisis K, Rugo HS, Yamashita T, Harbeck N, Im SA, De Laurentiis M, Pierga JY, Wang X, Gombos A, Tokunaga E, Orbegoso Aguilar C, Yung L, Xiao F, Cheng Y, Cameron D.   +24 more
europepmc   +1 more source

Recent Advances in Top‐Down Proteomics for Single‐Cell Research

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley   +1 more source

Evolving treatment strategies for HER2-altered non-small-cell lung cancer: the rise of TKIs and ADCs. [PDF]

Front Oncol
Balli S, Basoglu T, Ozdogan M.
europepmc   +1 more source

Quantification of 10B and 11B in Biological Samples in Translational Science and Clinical Applications for Boron Neutron Capture Therapy (BNCT)

Medicinal Research Reviews, EarlyView.
ABSTRACT Boron neutron capture therapy (BNCT) is a targeted radiotherapy that exploits the selective accumulation of the 10B isotope within tumors, followed by irradiation with low‐energy neutrons to induce high linear energy transfer particles with short path lengths, resulting in localized tumor cell destruction while sparing surrounding healthy ...
Christoph Selg, Wolfgang A. G. Sauerwein, Evamarie Hey‐Hawkins   +2 more
wiley   +1 more source

The somatization of structural friction: deciphering the surge of adolescent self-harm in post-transition China. [PDF]

Front Psychiatry
Yan WJ, Ruan QN, Xu D.
europepmc   +1 more source

Shaping Manager Well‐Being and Functioning in Declining Nonprofit Organizations: The Critical Role of Strategy Implementation

Nonprofit Management and Leadership, EarlyView.
ABSTRACT Under the roof of Christian churches in Central Europe, some nonprofit organizations (NPOs) grow, while others are in marked decline. Our study in this context extends a previous focus on financial indicators to NPO managers' experiences, their role clarity and job satisfaction, during phases of organizational growth and decline. Specifically,
Max Niehoff, Johannes Stark
wiley   +1 more source

Trastuzumab deruxtecan in patients from China with previously treated human epidermal growth factor receptor 2-positive locally advanced/metastatic gastric or gastroesophageal junction adenocarcinoma (DESTINY-Gastric06): results from a single-arm, multicenter, phase 2 trial. [PDF]

EClinicalMedicine
Peng Z, Chen P, Lu J, Wan Y, Zheng Y, Ye F, Yang J, Liu Y, Pan H, Sun M, Fan Q, Yuan Y, Chen K, Sun Z, Tian H, Xia Y, Shen L.   +16 more
europepmc   +1 more source

Fruit‐quality tradeoffs generate asymmetry in plant reliance on mutualistic frugivores

Oikos, EarlyView.
Seed dispersal is a fundamental ecological process influencing the evolution of plant life‐history strategies. In fleshy‐fruited plants dispersed by mutualistic frugivores, variation in fruit traits among closely related species may shape the temporal and spatial dynamics of dispersal events critical to population success.
João Vitor S. Messeder, Tomás A. Carlo
wiley   +1 more source