Results 31 to 40 of about 7,320 (297)

« Couto Mixto » : ombilic et limbe ibérique

open access: yesCatalonia, 2020
Germs and ambivalences of the symbolic capitality of Couto Mixto, a historic enclave between Spain and Portugal, symbolizing through its historical destiny and its current rediscovery, an Iberian continuum and the buried conflicts of Galician identity ...
Benito Barja
doaj   +1 more source

Il medioevo citato di Giovanni Pascoli. Re Enzo fra storia e simbolo [PDF]

open access: yesParole Rubate, 2019
This essay examines Giovanni Pascoli’s Canzoni di Re Enzio within the nineteenth-century context of medieval revival. Far from stylizations and adaptations, the philological precision of the evocation of historical facts is linked to the tragedy of human
Francesca Irene Sensini
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Shared destiny: China story yearbook 2014

open access: yes, 2015
Humanity as never before shares a common destiny, whether it be in terms of the resources of the planet, the global environment, economic integration, or the movement of peoples, ideas, cultures.
Jeremy Goldkorn   +2 more
core   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Soviet man as a construct and a practice (from the history of interethnic relations in Akmolinsk)

open access: yesRUDN journal of Sociology, 2023
The article considers the concept of “a new historical community - the Soviet people” as a theoretical construction and a life practice. The authors analyze the terms “Soviet people”, “nation”, “nationality”, stressing that they have not received a ...
N. S. Kirabaev, J. S. Beisova
doaj   +1 more source

The Destiny of Man

open access: yes, 2009
In 1884, American historian and philosopher John Fiske published The Destiny of Man, which discussed humanity's origin, destiny and place in the universe.
John Fiske
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Dreams of Destiny and Omens of Greatness: Exceptionalism in Ottoman Political and Historical Thought [PDF]

open access: yesJournal of Islamic Studies, 2019
Abstract This article uses dreams, portents, and prognostications as an entry point into what some scholars have recently called ‘Ottoman exceptionalism’. Drawing on sources in Turkish and Arabic, it traces beliefs about the Ottoman dynasty and empire’s superiority, divine favour, and special role in history from the fifteenth to the ...
openaire   +1 more source

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