Results 41 to 50 of about 191,461 (306)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Quantitative Research on Historic City Landscape Value Assessment Based on AHP-GIS

Taiyuan Ligong Daxue xuebao, 2021
The historic urban landscape (HUL) concept is a protection concept proposed for the “continuous” change characteristics and “layered” presentation of cultural landscapes in cities in time series.
Zexin LEI, Junjie LUO, Lei CAO
doaj   +1 more source

Historical Maps in GIS

Geographic Information Science & Technology Body of Knowledge, 2019
This chapter offers an overview on the use of historical maps in GIS for the study of environment and landscape. The chapter starts with an introduction on the value of historical maps, their “definition” and a short review of the main types of historical maps that can be useful in a GIS analysis.
openaire   +2 more sources

DEVELOPMENT OF ETHNO-POLITICAL HISTORICAL GIS

Interexpo GEO-Siberia, 2020
The article deals with the development of methods of historical ethnopolitical GIS that integrates information about states, peoples, and localities on the territory of the Novosibirsk region at the end of the III century BC - XVI century AD. The process of implementing the project of this GIS is described on the example of a technological scheme of ...
Roman N. Batalov, Lyudmila K. Radchenko
openaire   +1 more source

HISTORY, MEMORY AND GEOGRAPHY - AN HISTORICAL GIS ON THE OPERATION OF THE ITALIAN ARMY DURING THE RUSSIAN CAMPAIGN (1941-1943) [PDF]

, 2010
Attraverso l’analisi di documentazione testuale e cartografica, è stata realizzata una ricostruzione dinamica degli eventi legati alla partecipazione dell’Italia all’invasione nazista della Russia.
De Santis, Valentina, Di Franco, Sabina, Plini, Paolo, Salvatori, Rosamaria   +3 more
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

GIS METHODS AND ANALYSIS OF ARCHAEOLOGICAL LAYERS IN THE TOPLICA DISTRICT (SERBIA)

Zbornik Radova: Geografski institut "Jovan Cvijić", 2019
In this paper, we are explaining a decade long investigation of historical, sacral and archaeological sites in the Toplica District (Serbia) as one of the significant cultural heritage sites in Europe with more than 226 objects with different time of ...
Aleksandar Valjarević, Žarko Mijajlović, Dragica Živković, Maja Novović, Marija Mihajlović   +4 more
doaj   +3 more sources

Multi-hazard risk assessment using GIS in urban areas: a case study for the city of Turrialba, Costa Rica [PDF]

, 2002
In the framework of the UNESCO sponsored project on “Capacity Building for Natural Disaster Reduction” a case study was carried out on multi-hazard risk assessment of the city of Turrialba, located in the central part of Costa Rica.
Badilla Coto, Elena, Boerboom, Luc, Montoya, Lorena, Westen, Cees J. van   +3 more
core   +6 more sources

Creating a common symbol classification for a new historical geoportal of Poland

Miscellanea Geographica: Regional Studies on Development, 2014
The crowd-sourcing approach should be implemented into a new historical geoportal of Poland due to its increasing potential in WebGIS. Registered users will be able to acquire spatial data from various map series.
Panecki Tomasz
doaj   +1 more source

Bridging the Past and Present: A GIS-Based System for Managing Ankara’s Multi-Layered Urban Heritage [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Cities that have been continuously inhabited and embody the spatial traces of historical continuity are defined as “multi-layered”. The remnants of historical periods and cultures, which constitute the stratified layers of the city and the ...
Z. B. Üstün, A. G. Bilgin Altınöz
doaj   +1 more source