Results 41 to 50 of about 202,912,194 (286)

Unlocking Historical Clinical Trial Data with ALIGN: A Compositional Large Language Model System for Medical Coding

CoRR
The reuse of historical clinical trial data has significant potential to accelerate medical research and drug development. However, interoperability challenges, particularly with missing medical codes, hinders effective data integration across studies.
Nabeel Seedat, Caterina Tozzi, Andrea Hita Ardiaca, Mihaela van der Schaar, James Weatherall, Adam Taylor   +5 more
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

An initial population parameter estimation of Portunus pelagicus on the eastern coast of Aceh [PDF]

BIO Web of Conferences
Conventional stock assessment models require large amounts of historical catch and effort data, which are often unavailable for small-scale fisheries such as the blue swimming crab (Portunus pelagicus) fishery on the east coast of Aceh. The lack of stock
Damora Adrian, Ramadhaniaty Mutia, Muhammad Razi Nanda, Pradana Hengki, Salsabila Zahra, Irfanda Asrul, Gustiva Tria, Fadli Nur   +7 more
doaj   +1 more source

Too hot, too cold, or just right: Can wildfire restore dry forests of the interior Pacific Northwest?

PLoS ONE, 2023
As contemporary wildfire activity intensifies across the western United States, there is increasing recognition that a variety of forest management activities are necessary to restore ecosystem function and reduce wildfire hazard in dry forests. However,
Skye M Greenler, Christopher J Dunn, James D Johnston, Matthew J Reilly, Andrew G Merschel, R Keala Hagmann, John D Bailey   +6 more
doaj   +1 more source

Predictive Modeling Using a Composite Index of Sleep and Cognition in the Alzheimer’s Continuum: A Decade-Long Historical Cohort Study

Journal of Alzheimer's Disease Reports
Background: Sleep disturbances frequently affect Alzheimer’s disease (AD), with up to 65% patients reporting sleep-related issues that may manifest up to a decade before AD symptoms. Objective: To construct a nomogram that synthesizes ...
Yu, Xianfeng, Deng, Shuqing, Liu, Junxin, Zhang, Mingkai, Zhang, Liang, Li, Ruixian, Zhang, Wei, Han, Ying   +7 more
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Automated Compositional Change Detection in Saxo Grammaticus’ Gesta Danorum

Digital Humanities in the Nordic and Baltic Countries Publications, 2019
Saxo Grammaticus’ medieval source Gesta Danorum (“Deeds of the Danes”) represents the beginning of the modern historical research in Denmark. The bipartite composition of Gesta Danorum has however been subject to much academic debate. In particular the
Kristoffer L. Nielbo, Mads L. Perner, Christian Larsen, Jonas Nielsen, Ditte Laursen   +4 more
doaj   +1 more source

Bess Model for Composite Reliability Assessment by Non-Sequential Monte Carlo Simulation Based on Historic or Synthetic Data

Energies
Battery Energy Storage System (BESS) models for reliability evaluation, as well as other power system simulation studies, are typically characterized by two key variables: State of Charge (SOC), representing the stored energy in MWh, and Injected Power (PB), indicating charging or discharging power in MW.
Djalma Falcão, Mateus Vaz, Thiago Masseran, Carmen Borges, Paulo Esmeraldo, João Aires, Tiago Amaral, Vinicius Lopes, Roberta Souza, Claudio Carvalho   +9 more
openaire   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

JAC: A Journal of Composition Theory

, 2011
JAC: A Journal of Composition Theory contains a collection of papers regarding writing and rhetoric: "The JAC is a forum for theory, research and pedagogy regarding (1) those writing courses beyond the freshman courses, excluding technical and creative ...
Worsham, Lynn, Association of Teachers of Advanced Composition (U.S.)   +1 more
core   +1 more source