Results 51 to 60 of about 202,912,194 (286)
What can community ecologists learn from species distribution models?
Ecosphere, 2021 Species distribution and ecological niche models (SDMs and ENMs) are popular tools used in a wide variety of research and conservation applications. However, their use in understanding community‐level patterns and processes is an emerging and rapidly ...
Stephen J. Murphy, Adam B. Smith
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
JAC: A Journal of Composition Theory
, 2009 JAC: A Journal of Composition Theory contains a collection of papers regarding writing and rhetoric: "The JAC is a forum for theory, research and pedagogy regarding (1) those writing courses beyond the freshman courses, excluding technical and creative ...
Worsham, Lynn +1 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Historical and theoretical foundations of the relationship between myth and literature [PDF]
Sinteze, 2012 This paper provides an overview of major mythological, anthropological, ethnological, sociological, philosophical and psychological theories and systems, as well as mythologists whose investigations attest to deep interconnectedness between literature ...
Marković Ana
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FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Journal of Advanced Composition
, 1980 The Journal of Advanced Composition contains a collection of papers regarding writing and rhetoric: "The JAC is a forum for theory, research and pedagogy regarding (1) those writing courses beyond the freshman courses, excluding technical and creative ...
Association of Teachers of Advanced Composition (U.S.)
core
Scientific Art in Glass: Archaeometric Analysis and Conservation of Blaschka Models
HeritageLeopold Blaschka (1822–1895) and his son Rudolf (1857–1939) created scientifically accurate glass models of marine invertebrates that reshaped natural history education in the 19th century.
Gemma Giani +8 more
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source