Results 21 to 30 of about 1,448,091 (219)
Transportation of hazardous materials via pipeline. A historical overview [PDF]
, 2018 The transportation of hazardous materials via pipelines is often considered a safer alternative to other transportation modalities such as railway, road and ship. However, pipelines often cross industrial and highly populated areas, so that their failure
Bubbico, R. +3 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A short historical overview on the use of lead [PDF]
, 2018 This historical introduction to the use of lead in art and technology was originally written to give context to lead conservation studies by the authors.
Adriaens, Mieke +2 more
core +1 more source
Historical Overview: The Parliamentary Library from Past to Present [PDF]
, 2010 Parliamentary libraries (also known under various terminologies such as federal libraries, legislative libraries, information resource centers, documentation centers, or reference services) enhance the research and information capacity of parliaments.
Anghelescu, Hermina G.B.
core +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Food Surpluses and Food Insecurity [PDF]
, 2007 Provides a historical overview of Israeli agricultural policy and examines the paradox of the creation and destruction of agricultural surpluses.
Sharon Ouziely
core
Bantu lexical reconstruction [PDF]
, 2016 Lexical reconstruction has been an important enterprise in Bantu historical linguistics since the earliest days of the discipline. In this chapter a historical overview is provided of the principal scholarly contributions to that field of study.
Bastin, Yvonne, Bostoen, Koen
core +2 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source