Results 41 to 50 of about 108,254 (253)
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
A NUTRITION OVERVIEW THROUGH CENTURIES. THE PRESENT-DAY NEED OF NUTRITIONAL EDUCATION IN SCHOOLS [PDF]
Challenges of the Knowledge Society, 2015 The type of alimentation and the food quality of individuals has undergone remarkable changes along with the progress of the human species. This study contains an historical overview regarding human nutrition from the primitive forms until the paradoxes ...
Simona ILAŞ
doaj
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Ecology and Society, 2017 Today's global challenges (e.g., food security) are not unprecedented in human history. Starting with the Neolithic transition, the agricultural sector and society underwent several cultural and technological changes and endured natural challenges. These
Sandra Teuber +5 more
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Knjižnica, 2006 The article describes further efforts to implement library automation in the Slovene National and University Library and other libraries in the period from 1977 to 1979.
Stanislav Bahor
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Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Hungarian spirits pálinka as a “Hungaricum” I. Literature review and practical approaches
Apstract: Applied Studies in Agribusiness and Commerce, 2014 The history of alcoholic distillation dates back over thousands of years. Spirits arrived in Hungary by the mediation of foreign countries, and were used as medicine in the royal court already in the XIV. Century.
Imre Milán Harcsa +2 more
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