Results 51 to 60 of about 101,140 (254)

Hungarian spirits pálinka as a “Hungaricum” I. Literature review and practical approaches

open access: yesApstract: Applied Studies in Agribusiness and Commerce, 2014
The history of alcoholic distillation dates back over thousands of years. Spirits arrived in Hungary by the mediation of foreign countries, and were used as medicine in the royal court already in the XIV. Century.
Imre Milán Harcsa   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Solar models: An historical overview

open access: yesNuclear Physics B - Proceedings Supplements, 2003
I will summarize in four slides the 40 years of development of the standard solar model that is used to predict solar neutrino fluxes and then describe the current uncertainties in the predictions. I will dispel the misconception that the p-p neutrino flux is determined by the solar luminosity and present a related formula that gives, in terms of the ...
openaire   +2 more sources

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Comparative construction and/or construction of manner from Vuk S. Karadžic to the present [PDF]

open access: yesBaština, 2019
The paper will deal with terminology, (sub) types and the use of comparative and methodical sentences (and constructions) in the past two centuries, from Vuk's first grammar (1814) through the Serbian Dictionaries by Vuk S. Karadžić (I - 1818; II - 1852)
Spasić Nataša A.
doaj  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A brief review of plagiarism in medical scientific research papers

open access: yesPharmaceutical and Biomedical Research, 2016
Plagiarism refers to “adopting someone else’s words, work or ideas and passing them off as one’s own”. It is potentially considered as the most prevalent form of scientific dishonesty discovered in research papers.
Mohammad Karami, Gholam Hassan Danaei
doaj  

Atypical melanocytic lesions: a historical overview

open access: yesPolish Journal of Pathology, 2019
The distinction between atypical Spitz lesions, conventional melanocytic nevi including Spitz nevi, and malignant melanomas may be difficult in some cases or may even be impossible.
Melissa Manchi, Vincenzo Canzonieri
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Changing Principles How To Define and Regulate the Term ‘Industrial Park’: The Case of Hungary, Romania and Bulgaria

open access: yesDETUROPE, 2015
The development of industrial parks began in the 1960s with the transformation of previous production systems and the technological change. Initially, the first industrial areas were developed spontaneously when positive externalities rose from the close
Lívia Ablonczy-Mihályka   +1 more
doaj  

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