Results 101 to 110 of about 1,646,641 (334)

Historical and paleo-tsunami deposits on Kamchatka, Russia: long-term chronologies and long-distance correlations [PDF]

open access: yesNatural Hazards and Earth System Sciences, 2001
Along the eastern coast of Kamchatka, at a number of localities, we have identified and attempted to assign ages to deposits of both historic and prehistoric (paleo-) tsunamis.
T. K. Pinegina, J. Bourgeois
doaj  

Strathconon, Scatwell and the Mackenzies in the Written Record c. 1463-c.1700 [PDF]

open access: yes, 2010
Although some writers have considered the earlier history of Ross, these studies tend to focus on dynastic and political events and not much is know about the internal workings of Ross-shire far less Strathconon in the historical record prior to the end ...
Maccoinnich, Aonghas
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Conference Review: Fifth International Congress of Experimental Archaeology, Tarragona (Spain), October 2017

open access: yesEXARC Journal, 2018
Experimental archaeology is an important methodological resource for academic and historical scientific research, not separated from the rest of archaeological and historical sciences, and usually used to interpret the formation of the archaeological ...
Francesca Romagnoli   +1 more
doaj  

Preserving newspapers: National and international cooperative efforts [PDF]

open access: yes, 1991
Historians have always turned to newspapers to see how events were interpreted at the time that they occurred. Now, more than ever, with an increased interest in social history and in the daily life of the common person, historians have come to ...
Swartzburg, Susan Garrison
core  

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Historical rainstorm in Hong Kong on 7–8 September 2023: Diagnosis, forecasting and nowcasting

open access: yesAtmospheric Science Letters
On 7–8 September 2023, Hong Kong was hit by a historical and record‐breaking rainstorm associated with the remnant of Tropical Cyclone Haikui (2311).
Hiu Ching Tam   +7 more
doaj   +1 more source

A large unknown historical earthquake in the Abruzzi region (Central Italy): combination of geological and historical data

open access: yesAnnals of Geophysics, 1995
The combination of paleoseismological and historical investigation can be used to obtain a complete knowledge of past earthquakes. In Italy the 1000 year-long record of historical earthquakes provides an opportunity to compare data from the catalogue ...
D. Pantosti, F. R. Cinti, G. D'Addezio
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

LOWER NORTH BATTERY - DEFENDED PORT OF SIMON'S TOWN

open access: yesScientia Militaria, 2012
In 1975 Mr H. C. Willis suggested to the present writer that the SA Navy should mount a bronze plaque similar to those commissioned by the Simon's Town Historical Society and displayed on certain historical buildings in the town at Lower North Battery to
W.M. Bisset
doaj   +1 more source

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