Results 81 to 90 of about 60,652 (299)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Historical Roots of the Dutch Sustainability Challenge
, 2012 Database on materials flows in the Dutch economy: 1850-1910-1970-2005 This study starts from two main concerns: - What are the historical roots of the current sustainability problems of the Netherlands?
Lintsen, H.W. +4 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Kent Historical Society Quarterly Bulletin, Volume 20, September 1995
, 1995 KENT HISTORICAL SOCIETY 152 Franklin Avenue, P.O. Box 663, Kent, Ohio 44240- (216) 678-2712 Volume 20 - September 1995 HEALTHY TRANSPORTATION WEEK COMES TO KENT September 16 - 23 In keeping with the educational goals of the Kent Intermodal Transportation
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
, 1930 A group of Roots Store employees gathers outside the front entrance for a group portrait.This image is a preservation copy made from an unstable original nitrate ...
Martin's Photo Shop
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Green and sustainable business models: historical roots, growth trajectory, conceptual architecture and an agenda for future research-A bibliometric review of green and sustainable business models. [PDF]
Scientometrics, 2023 Najmaei A, Sadeghinejad Z.
europepmc +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Historical roots of extremist narratives in Europe
Bauvois is co-athor and co-oordinator of the Gender section of this report on the Historical Roots of Extremist Narratives. This report delves into the historical roots and evolution of extremist narratives in Europe, spanning from the late 19th century ...
Bauvois, Gwenaëlle
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