Results 241 to 250 of about 1,885,281 (312)

Study on the differentiated impact of climate change on plague epidemics in Northern and Southern China, 1912-1949. [PDF]

PLoS Negl Trop Dis
Zhang L, Yin S, Ge M, Pang L.
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Microbial Primer: Ancientbiotics - making modern antimicrobials from historical infection remedies. [PDF]

Microbiology (Reading)
Harrison F, Orababa OQ.
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Longitudinal clinical and preclinical studies identify hetrombopag as a potent chelator for systemic iron overload. [PDF]

Hemasphere
Zhao Y, Xing L, Zhang B, Yang W, Hu X, Liu X, Yang X, Liang W, Shi Y, Hu J, Li X, Kang R, Peng G, Li Y, Hu X, Xiong Y, Jing L, Yuan W, Li S, Zhang F, Zhao X.   +20 more
europepmc   +1 more source

HISTORICAL SOURCE AND SECONDARY KNOWLEDGE IN HISTORICAL SCIENCE

Vestnik Tomskogo gosudarstvennogo universiteta, 2015
openaire   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Comparative study of bioclimatic conditions in southwestern Greenland between the late 18th century and the present. [PDF]

Int J Biometeorol
Araźny A, Chmist K, Przybylak R, Wyszyński P, Singh G.   +4 more
europepmc   +1 more source

Km-scale coupled simulation and model-observation SST trend discrepancy. [PDF]

Proc Natl Acad Sci U S A
Kang SM, Putrasahan DA, Brizuela NG, Haak H, Kröger J, Marotzke J, Stevens B, von Storch JS.   +7 more
europepmc   +1 more source