Results 101 to 110 of about 2,484,825 (307)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The American Historical Review, 1921 "Reprinted from the American historical review. Vol. XXVI, no. 4. July, 1921." ; Cover title. ; Mode of access: Internet.
openaire +2 more sources
The Disingenuousness of the Jesus Legend in Popular Media [PDF]
, 2016 In America today, a major source of contention among theologians involves the Resurrection, a controversy that has ensued since historical times (1 Cor 15: 12-19 [KJV]).
Louie, Emma L
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Russian Diaries and Memoirs about War for Polish Succession (1733-1735) as Historical Sources
Научный диалог, 2018 The article is devoted to the use of diaries and memoirs as historical sources in the study of the war for the Polish Succession of 1733-1735. Relevance of present research is explained by low degree of studying of the given military conflict in the ...
O. V. Saprikina, K. M. Belyukov
doaj +1 more source
Land use change detection with LANDSAT-2 data for monitoring and predicting regional water quality degradation [PDF]
The author has identified the following significant results. Comparison between LANDSAT 1 and 2 imagery of Arkansas provided evidence of significant land use changes during the 1972-75 time period.
Dillard, T. +6 more
core +1 more source
About the holding status of Manchu and Chinese materials [PDF]
, 2020 Manchu and Chinese texts are a very useful source of historical research on Chinese linguistics. From the viewpoint of language contact, there is a great influence on each language. Chinese in the Qing dynasty is clearly influenced by the Manchu language,
Uchida Keiichi, 内田 慶市
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source