Results 41 to 50 of about 244,749 (267)
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
On S.F. Platonov's review of V.G. Druzhinin's book
This article considers, with the involvement of archival materials introduced into scientific use for the first time, an unknown fact with S.F. Platonov’s unfinished review of the book by V.G. Druzhinin, which originated from his master’s thesis.
V.V. Mitrofanov
doaj +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
History and Truth: the interaction possibilities of theological and historical methodologies [PDF]
In the given text the author attempts to offer a statement of the question about relations between theological and historical methodologies. Universal categories - History and Truth - work as a general scheme of discourse.
Mikhailov Petr
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The paper provides an assessment of journalism as a historical source for studying the problems of contemporary Russian History. The development stages and genres of journalism are defined and characterized.
K. A. Zabolotskaya
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Статья посвящена истории атрибуции вазы из фонда художественной керамики и стекла Омского областного музея изобразительных искусств имени М.А. Врубеля. Актуальность исследования определена необходимостью атрибуции, систематизации, каталогизации музейных ...
Ермола, М.В.
doaj +1 more source

