Results 61 to 70 of about 244,749 (267)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Monograph Review by: Dolgikh A.N. (2024). “But a Terrible Thought Darkens the Soul Here...”: The Problem of Serfdom in the Works of Russian Writers of the 18th – first half of the 19th Centuries. Historiographical Essays. Lipetsk, Lipetsk State Pedagogical P. Semenov-Tyan-Shansky University Publ., 365 p.

open access: yesВестник Тамбовского университета. Серия: Гуманитарные науки
Importance. The scientific significance of the publication is related to the need to constantly emphasize the studying fiction importance as a valuable historical source.Materials and Methods. The historiographical source is a monograph by A.N.
V. V. Kanishchev
doaj   +1 more source

Sources on the History of Ethnic Entrepreneurship of the Republic of Adygea and the Black Sea in the Early 1990s

open access: yesНаучный диалог, 2019
The necessity of expanding the corpus of sources is substantiated when analyzing the processes of forming entrepreneurship in the early 1990s among ethnic groups of the Adygei of the Republic of Adygea and the Black Sea coast of the Caucasus (Shapsugs ...
M. V. Belozerova
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

History of Tourism Development in Shoria Mountains (1999–2010): The Krasnaya Shoria Newspaper

open access: yesСибСкрипт
As the Kemerovo Region adds its touristic capacity, the local tourism industry needs scientific approach to its most relevant issues, and local periodicals can provide a lot of useful information in this respect.
Ekaterina A. Filonova
doaj   +1 more source

Reflection of M. E. Saltykov-Shchedrin’s Works in V. I. Semevsky’s Researches about Serfdom and Peasant Question in Russia

open access: yesНаучный диалог, 2019
The study of the literary and journalistic image of serfdom and the peasant question in the works by M. E. Saltykov-Shchedrin, conducted by the prominent historian of the Russian peasantry V. I. Semevsky, is considered.
S. V. Gavrilov, I. A. Gavrilova
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Anecdote as a historical source (historiographic aspect)

open access: yesВестник Тамбовского университета. Серия: Гуманитарные науки
Importance. The anecdote is a unique historical source for Russian history, reflecting the population's distinctive mentality and a source for studying the history of everyday life. While there have been numerous studies devoted to various aspects of the
A. A. Demichev
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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